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A Series of 2-((1-Phenyl-1H-imidazol-5-yl)methyl)-1H-indoles as Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Zheng Y, Stafford PM, Stover KR, Mohan DC, Gupta M, Keske EC, Schiavini P, Villar L, Wu F, Kreft A, Thomas K, Raaphorst E, Pasangulapati JP, Alla SR, Sharma S, Mittapalli RR, Sagamanova I, Johnson SL, Reed MA, Weaver DF. Zheng Y, et al. Among authors: wu f. ChemMedChem. 2021 Jul 20;16(14):2195-2205. doi: 10.1002/cmdc.202100107. Epub 2021 May 26. ChemMedChem. 2021. PMID: 33759400
Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites.
Meier-Stephenson FS, Meier-Stephenson VC, Carter MD, Meek AR, Wang Y, Pan L, Chen Q, Jacobo S, Wu F, Lu E, Simms GA, Fisher L, McGrath AJ, Fermo V, Barden CJ, Clair HDS, Galloway TN, Yadav A, Campágna-Slater V, Hadden M, Reed M, Taylor M, Kelly B, Diez-Cecilia E, Kolaj I, Santos C, Liyanage I, Sweeting B, Stafford P, Boudreau R, Reid GA, Noyce RS, Stevens L, Staniszewski A, Zhang H, Murty MRVS, Lemaire P, Chardonnet S, Richardson CD, Gabelica V, DePauw E, Brown R, Darvesh S, Arancio O, Weaver DF. Meier-Stephenson FS, et al. Among authors: wu f. Alzheimers Dement (N Y). 2022 Apr 6;8(1):e12283. doi: 10.1002/trc2.12283. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35415204 Free PMC article.
Computer-aided drug design to generate a unique antibiotic family.
Barden CJ, Wu F, Fernandez-Murray JP, Lu E, Sun S, Taylor MM, Rushton AL, Williams J, Tavasoli M, Meek A, Reddy AS, Doyle LM, Sagamanova I, Sivamuthuraman K, Boudreau RTM, Byers DM, Weaver DF, McMaster CR. Barden CJ, et al. Among authors: wu f. Nat Commun. 2024 Sep 27;15(1):8317. doi: 10.1038/s41467-024-52797-2. Nat Commun. 2024. PMID: 39333560 Free PMC article.
Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation.
Huhe H, Shapley SM, Duong DM, Wu F, Ha SK, Choi SH, Kofler J, Mou Y, Guimaraes TR, Thathiah A, Watson CM, Schaeffer LKH, Carter GW, Seyfried NT, Silva AC, Sukoff Rizzo SJ. Huhe H, et al. Among authors: wu f. Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14366. Online ahead of print. Alzheimers Dement. 2024. PMID: 39559898
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