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187 results

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Comparative analysis of YAP/TEAD inhibitors in 2D and 3D cultures of primary human hepatocytes reveals a novel non-canonical mechanism of CYP induction.
Oliva-Vilarnau N, Vorrink SU, Büttner FA, Heinrich T, Sensbach J, Koscielski I, Wienke D, Petersson C, Perrin D, Lauschke VM. Oliva-Vilarnau N, et al. Among authors: lauschke vm. Biochem Pharmacol. 2023 Sep;215:115755. doi: 10.1016/j.bcp.2023.115755. Epub 2023 Aug 20. Biochem Pharmacol. 2023. PMID: 37607620 Free article.
Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.
Tredup C, Ndreshkjana B, Schneider NS, Tjaden A, Kemas AM, Youhanna S, Lauschke VM, Berger BT, Krämer A, Berger LM, Röhm S, Knapp S, Farin HF, Müller S. Tredup C, et al. Among authors: lauschke vm. ACS Chem Biol. 2023 Apr 21;18(4):822-836. doi: 10.1021/acschembio.2c00877. Epub 2023 Mar 21. ACS Chem Biol. 2023. PMID: 36944371 Free PMC article.
Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control.
Gineste C, Youhanna S, Vorrink SU, Henriksson S, Hernández A, Cheng AJ, Chaillou T, Buttgereit A, Schneidereit D, Friedrich O, Hultenby K, Bruton JD, Ivarsson N, Sandblad L, Lauschke VM, Westerblad H. Gineste C, et al. Among authors: lauschke vm. iScience. 2022 Nov 22;25(12):105654. doi: 10.1016/j.isci.2022.105654. eCollection 2022 Dec 22. iScience. 2022. PMID: 36479146 Free PMC article.
Bioengineered Pancreas-Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia.
Zandi Shafagh R, Youhanna S, Keulen J, Shen JX, Taebnia N, Preiss LC, Klein K, Büttner FA, Bergqvist M, van der Wijngaart W, Lauschke VM. Zandi Shafagh R, et al. Among authors: lauschke vm. Adv Sci (Weinh). 2022 Dec;9(34):e2203368. doi: 10.1002/advs.202203368. Epub 2022 Oct 26. Adv Sci (Weinh). 2022. PMID: 36285680 Free PMC article.
In vitro and ex vivo modeling of enteric bacterial infections.
Taebnia N, Römling U, Lauschke VM. Taebnia N, et al. Among authors: lauschke vm. Gut Microbes. 2023 Jan-Dec;15(1):2158034. doi: 10.1080/19490976.2022.2158034. Gut Microbes. 2023. PMID: 36576310 Free PMC article. Review.
Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment.
Turner J, Pound P, Owen C, Hutchinson I, Hop M, Chau DYS, Barrios Silva LV, Coleman M, Dubourg A, Harries LW, Hutter V, Kenna JG, Lauschke VM, Neuhaus W, Roper C, Watkins PB, Welch J, Alvarez LR, Taylor K. Turner J, et al. Among authors: lauschke vm. ALTEX. 2023;40(3):519-533. doi: 10.14573/altex.2212081. Epub 2023 Jan 18. ALTEX. 2023. PMID: 36692187 Free article.
187 results