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HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.
Kovalenko M, Milnerwood A, Giordano J, St Claire J, Guide JR, Stromberg M, Gillis T, Sapp E, DiFiglia M, MacDonald ME, Carroll JB, Lee JM, Tappan S, Raymond L, Wheeler VC. Kovalenko M, et al. Among authors: difiglia m. J Huntingtons Dis. 2018;7(1):17-33. doi: 10.3233/JHD-170282. J Huntingtons Dis. 2018. PMID: 29480209 Free PMC article.
Huntingtin associates with acidic phospholipids at the plasma membrane.
Kegel KB, Sapp E, Yoder J, Cuiffo B, Sobin L, Kim YJ, Qin ZH, Hayden MR, Aronin N, Scott DL, Isenberg G, Goldmann WH, DiFiglia M. Kegel KB, et al. Among authors: difiglia m. J Biol Chem. 2005 Oct 28;280(43):36464-73. doi: 10.1074/jbc.M503672200. Epub 2005 Aug 5. J Biol Chem. 2005. PMID: 16085648 Free article.
A function of huntingtin in guanine nucleotide exchange on Rab11.
Li X, Sapp E, Valencia A, Kegel KB, Qin ZH, Alexander J, Masso N, Reeves P, Ritch JJ, Zeitlin S, Aronin N, Difiglia M. Li X, et al. Among authors: difiglia m. Neuroreport. 2008 Oct 29;19(16):1643-7. doi: 10.1097/WNR.0b013e328315cd4c. Neuroreport. 2008. PMID: 18845944
Polyglutamine expansion in huntingtin alters its interaction with phospholipids.
Kegel KB, Sapp E, Alexander J, Valencia A, Reeves P, Li X, Masso N, Sobin L, Aronin N, DiFiglia M. Kegel KB, et al. Among authors: difiglia m. J Neurochem. 2009 Sep;110(5):1585-97. doi: 10.1111/j.1471-4159.2009.06255.x. Epub 2009 Jun 29. J Neurochem. 2009. PMID: 19566678 Free article.
Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease.
Li X, Sapp E, Chase K, Comer-Tierney LA, Masso N, Alexander J, Reeves P, Kegel KB, Valencia A, Esteves M, Aronin N, Difiglia M. Li X, et al. Among authors: difiglia m. Neurobiol Dis. 2009 Nov;36(2):374-83. doi: 10.1016/j.nbd.2009.08.003. Epub 2009 Aug 20. Neurobiol Dis. 2009. PMID: 19699304 Free PMC article.
193 results