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Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma.
McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer M, Thomas CJ, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA. McKinnon T, et al. Among authors: guha r. Oncogene. 2018 May;37(20):2630-2644. doi: 10.1038/s41388-017-0122-y. Epub 2018 Feb 28. Oncogene. 2018. PMID: 29487419 Free PMC article.
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.
Yohe ME, Gryder BE, Shern JF, Song YK, Chou HC, Sindiri S, Mendoza A, Patidar R, Zhang X, Guha R, Butcher D, Isanogle KA, Robinson CM, Luo X, Chen JQ, Walton A, Awasthi P, Edmondson EF, Difilippantonio S, Wei JS, Zhao K, Ferrer M, Thomas CJ, Khan J. Yohe ME, et al. Among authors: guha r. Sci Transl Med. 2018 Jul 4;10(448):eaan4470. doi: 10.1126/scitranslmed.aan4470. Sci Transl Med. 2018. PMID: 29973406 Free PMC article.
Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol.
Raj D, Nair AV, Singh A, Basu S, Sarkar K, Sharma J, Sharma S, Sharma S, Rathore M, Singh S, Prakash S, Simran, Sahu S, Kaushik AC, Siddiqi MI, Ghoshal UC, Chandra T, Bhosale V, Dasgupta A, Gupta SK, Verma S, Guha R, Chakravortty D, Ammanathan V, Lahiri A. Raj D, et al. Among authors: guha r. EMBO Rep. 2024 Dec 18. doi: 10.1038/s44319-024-00328-x. Online ahead of print. EMBO Rep. 2024. PMID: 39695325 Free article.
Mechanochemically accelerated deconstruction of chemically recyclable plastics.
Hua M, Peng Z, Guha RD, Ruan X, Ng KC, Demarteau J, Haber S, Fricke SN, Reimer JA, Salmeron MB, Persson KA, Wang C, Helms BA. Hua M, et al. Among authors: guha rd. Sci Adv. 2024 Sep 20;10(38):eadq3801. doi: 10.1126/sciadv.adq3801. Epub 2024 Sep 18. Sci Adv. 2024. PMID: 39292772 Free PMC article.
263 results