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IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
Ladomersky E, Zhai L, Lenzen A, Lauing KL, Qian J, Scholtens DM, Gritsina G, Sun X, Liu Y, Yu F, Gong W, Liu Y, Jiang B, Tang T, Patel R, Platanias LC, James CD, Stupp R, Lukas RV, Binder DC, Wainwright DA. Ladomersky E, et al. Among authors: gong w. Clin Cancer Res. 2018 Jun 1;24(11):2559-2573. doi: 10.1158/1078-0432.CCR-17-3573. Epub 2018 Mar 2. Clin Cancer Res. 2018. PMID: 29500275 Free PMC article.
BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Tang Z, Yuan X, Du R, Cheung SH, Zhang G, Wei J, Zhao Y, Feng Y, Peng H, Zhang Y, Du Y, Hu X, Gong W, Liu Y, Gao Y, Liu Y, Hao R, Li S, Wang S, Ji J, Zhang L, Li S, Sutton D, Wei M, Zhou C, Wang L, Luo L. Tang Z, et al. Among authors: gong w. Mol Cancer Ther. 2015 Oct;14(10):2187-97. doi: 10.1158/1535-7163.MCT-15-0262. Epub 2015 Jul 24. Mol Cancer Ther. 2015. PMID: 26208524
The binding of an anti-PD-1 antibody to FcγRΙ has a profound impact on its biological functions.
Zhang T, Song X, Xu L, Ma J, Zhang Y, Gong W, Zhang Y, Zhou X, Wang Z, Wang Y, Shi Y, Bai H, Liu N, Yang X, Cui X, Cao Y, Liu Q, Song J, Li Y, Tang Z, Guo M, Wang L, Li K. Zhang T, et al. Among authors: gong w. Cancer Immunol Immunother. 2018 Jul;67(7):1079-1090. doi: 10.1007/s00262-018-2160-x. Epub 2018 Apr 23. Cancer Immunol Immunother. 2018. PMID: 29687231 Free PMC article.
RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K-RAS mutant tumors.
Yuan X, Tang Z, Du R, Yao Z, Cheung SH, Zhang X, Wei J, Zhao Y, Du Y, Liu Y, Hu X, Gong W, Liu Y, Gao Y, Huang Z, Cao Z, Wei M, Zhou C, Wang L, Rosen N, Smith PD, Luo L. Yuan X, et al. Among authors: gong w. Mol Oncol. 2020 Aug;14(8):1833-1849. doi: 10.1002/1878-0261.12698. Epub 2020 May 18. Mol Oncol. 2020. PMID: 32336014 Free PMC article.
Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor.
Xiong Y, Guo Y, Liu Y, Wang H, Gong W, Liu Y, Wang X, Gao Y, Yu F, Su D, Wang F, Zhu Y, Zhao Y, Wu Y, Qin Z, Sun X, Ren B, Jiang B, Jin W, Shen Z, Tang Z, Song X, Wang L, Liu X, Zhou C, Jiang B. Xiong Y, et al. Among authors: gong w. Neoplasia. 2020 Sep;22(9):431-440. doi: 10.1016/j.neo.2020.06.009. Epub 2020 Jul 8. Neoplasia. 2020. PMID: 32652442 Free PMC article.
Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.
Wang H, Ren B, Liu Y, Jiang B, Guo Y, Wei M, Luo L, Kuang X, Qiu M, Lv L, Xu H, Qi R, Yan H, Xu D, Wang Z, Huo CX, Zhu Y, Zhao Y, Wu Y, Qin Z, Su D, Tang T, Wang F, Sun X, Feng Y, Peng H, Wang X, Gao Y, Liu Y, Gong W, Yu F, Liu X, Wang L, Zhou C. Wang H, et al. Among authors: gong w. J Med Chem. 2020 Dec 24;63(24):15541-15563. doi: 10.1021/acs.jmedchem.0c01346. Epub 2020 Dec 2. J Med Chem. 2020. PMID: 33264017
BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models.
Jiang B, Zhang T, Deng M, Jin W, Hong Y, Chen X, Chen X, Wang J, Hou H, Gao Y, Gong W, Wang X, Li H, Zhou X, Feng Y, Zhang B, Jiang B, Lu X, Zhang L, Li Y, Song W, Sun H, Wang Z, Song X, Shen Z, Liu X, Li K, Wang L, Liu Y. Jiang B, et al. Among authors: gong w. Front Med. 2023 Dec;17(6):1170-1185. doi: 10.1007/s11684-023-0996-8. Epub 2023 Sep 25. Front Med. 2023. PMID: 37747585
Tumor burden with AFP improves survival prediction for TACE-treated patients with HCC: An international observational study☆.
Xia D, Bai W, Wang Q, Chung JW, Adhoute X, Kloeckner R, Zhang H, Zeng Y, Sripongpun P, Nie C, Kim SU, Huang M, Hu W, Ding X, Yin G, Li H, Zhao H, Bronowicki JP, Li J, Li J, Zhu X, Wu J, Zhang C, Gong W, Li Z, Lin Z, Xu T, Yin T, Anty R, Song J, Shi H, Shao G, Ren W, Zhang Y, Yang S, Zheng Y, Xu J, Wang W, Zhu X, Fu Y, Liu C, Kaewdech A, Ding R, Zheng J, Liu S, Yu H, Zheng L, You N, Fan W, Zhang S, Feng L, Wang G, Zhang P, Li X, Chen J, Zhang F, Shao W, Zhou W, Zeng H, Cao G, Huang W, Jiang W, Zhang W, Li L, Feng A, Wang E, Wang Z, Han D, Lv Y, Sun J, Ren B, Xia L, Li X, Yuan J, Wang Z, Luo B, Li K, Guo W, Yin Z, Zhao Y, Xia J, Fan D, Wu K, Bettinger D, Vogel A, Han G; China HCC-TACE study group. Xia D, et al. Among authors: gong w. JHEP Rep. 2024 Sep 12;7(1):101216. doi: 10.1016/j.jhepr.2024.101216. eCollection 2025 Jan. JHEP Rep. 2024. PMID: 39758510 Free PMC article.
4,729 results