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Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform.
Norcliffe JL, Mina JG, Alvarez E, Cantizani J, de Dios-Anton F, Colmenarejo G, Valle SG, Marco M, Fiandor JM, Martin JJ, Steel PG, Denny PW. Norcliffe JL, et al. Among authors: steel pg. Sci Rep. 2018 Mar 2;8(1):3938. doi: 10.1038/s41598-018-22063-9. Sci Rep. 2018. PMID: 29500420 Free PMC article.
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.
Mina JG, Pan SY, Wansadhipathi NK, Bruce CR, Shams-Eldin H, Schwarz RT, Steel PG, Denny PW. Mina JG, et al. Among authors: steel pg. Mol Biochem Parasitol. 2009 Nov;168(1):16-23. doi: 10.1016/j.molbiopara.2009.06.002. Epub 2009 Jun 21. Mol Biochem Parasitol. 2009. PMID: 19545591 Free article.
79 results