Burr SP - Search Results

1

Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions.

Bargiela D, Burr SP, Chinnery PF. Bargiela D, et al. Among authors: burr sp. Trends Endocrinol Metab. 2018 Apr;29(4):249-259. doi: 10.1016/j.tem.2018.02.002. Epub 2018 Feb 28. Trends Endocrinol Metab. 2018. PMID: 29501229 Review.

2

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.

Burr SP, Costa AS, Grice GL, Timms RT, Lobb IT, Freisinger P, Dodd RB, Dougan G, Lehner PJ, Frezza C, Nathan JA. Burr SP, et al. Cell Metab. 2016 Nov 8;24(5):740-752. doi: 10.1016/j.cmet.2016.09.015. Epub 2016 Oct 27. Cell Metab. 2016. PMID: 27923773 Free PMC article.

3

Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line.

Burr SP, Pezet M, Chinnery PF. Burr SP, et al. Dev Growth Differ. 2018 Jan;60(1):21-32. doi: 10.1111/dgd.12420. Epub 2018 Jan 24. Dev Growth Differ. 2018. PMID: 29363102 Free PMC article. Review.

4

The mitochondrial DNA genetic bottleneck: inheritance and beyond.

Zhang H, Burr SP, Chinnery PF. Zhang H, et al. Among authors: burr sp. Essays Biochem. 2018 Jul 20;62(3):225-234. doi: 10.1042/EBC20170096. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 29880721 Review.

5

Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro.

Pezet MG, Gomez-Duran A, Klimm F, Aryaman J, Burr S, Wei W, Saitou M, Prudent J, Chinnery PF. Pezet MG, et al. Commun Biol. 2021 May 14;4(1):584. doi: 10.1038/s42003-021-02069-2. Commun Biol. 2021. PMID: 33990696 Free PMC article.

6

Mitochondrial DNA heteroplasmy is modulated during oocyte development propagating mutation transmission.

Zhang H, Esposito M, Pezet MG, Aryaman J, Wei W, Klimm F, Calabrese C, Burr SP, Macabelli CH, Viscomi C, Saitou M, Chiaratti MR, Stewart JB, Jones N, Chinnery PF. Zhang H, et al. Among authors: burr sp. Sci Adv. 2021 Dec 10;7(50):eabi5657. doi: 10.1126/sciadv.abi5657. Epub 2021 Dec 8. Sci Adv. 2021. PMID: 34878831 Free PMC article.

7

Measuring Single-Cell Mitochondrial DNA Copy Number and Heteroplasmy using Digital Droplet Polymerase Chain Reaction.

Burr SP, Chinnery PF. Burr SP, et al. J Vis Exp. 2022 Jul 12;(185). doi: 10.3791/63870. J Vis Exp. 2022. PMID: 35913155

8

Cell lineage-specific mitochondrial resilience during mammalian organogenesis.

Burr SP, Klimm F, Glynos A, Prater M, Sendon P, Nash P, Powell CA, Simard ML, Bonekamp NA, Charl J, Diaz H, Bozhilova LV, Nie Y, Zhang H, Frison M, Falkenberg M, Jones N, Minczuk M, Stewart JB, Chinnery PF. Burr SP, et al. Cell. 2023 Mar 16;186(6):1212-1229.e21. doi: 10.1016/j.cell.2023.01.034. Epub 2023 Feb 23. Cell. 2023. PMID: 36827974 Free article.

9

High-throughput single-cell analysis reveals progressive mitochondrial DNA mosaicism throughout life.

Glynos A, Bozhilova LV, Frison M, Burr S, Stewart JB, Chinnery PF. Glynos A, et al. Sci Adv. 2023 Oct 27;9(43):eadi4038. doi: 10.1126/sciadv.adi4038. Epub 2023 Oct 25. Sci Adv. 2023. PMID: 37878704 Free PMC article.

10

Origins of tissue and cell-type specificity in mitochondrial DNA (mtDNA) disease.

Burr SP, Chinnery PF. Burr SP, et al. Hum Mol Genet. 2024 May 22;33(R1):R3-R11. doi: 10.1093/hmg/ddae059. Hum Mol Genet. 2024. PMID: 38779777 Free PMC article. Review.

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