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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.
Badders NM, Korff A, Miranda HC, Vuppala PK, Smith RB, Winborn BJ, Quemin ER, Sopher BL, Dearman J, Messing J, Kim NC, Moore J, Freibaum BD, Kanagaraj AP, Fan B, Tillman H, Chen PC, Wang Y, Freeman BB III, Li Y, Kim HJ, La Spada AR, Taylor JP. Badders NM, et al. Among authors: taylor jp. Nat Med. 2018 May;24(4):427-437. doi: 10.1038/nm.4500. Epub 2018 Mar 5. Nat Med. 2018. PMID: 29505030 Free PMC article.
Polyglutamines placed into context.
La Spada AR, Taylor JP. La Spada AR, et al. Among authors: taylor jp. Neuron. 2003 Jun 5;38(5):681-4. doi: 10.1016/s0896-6273(03)00328-3. Neuron. 2003. PMID: 12797953 Free article. Review.
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, Padmanabhan R, Hild M, Berry DL, Garza D, Hubbert CC, Yao TP, Baehrecke EH, Taylor JP. Pandey UB, et al. Among authors: taylor jp. Nature. 2007 Jun 14;447(7146):859-63. doi: 10.1038/nature05853. Nature. 2007. PMID: 17568747
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP. Kim HJ, et al. Among authors: taylor jp. Nature. 2013 Mar 28;495(7442):467-73. doi: 10.1038/nature11922. Epub 2013 Mar 3. Nature. 2013. PMID: 23455423 Free PMC article.
592 results