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Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.
Hill PWS, Leitch HG, Requena CE, Sun Z, Amouroux R, Roman-Trufero M, Borkowska M, Terragni J, Vaisvila R, Linnett S, Bagci H, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, Pradhan S, Hajkova P. Hill PWS, et al. Among authors: requena ce. Nature. 2018 Mar 15;555(7696):392-396. doi: 10.1038/nature25964. Epub 2018 Mar 7. Nature. 2018. PMID: 29513657 Free PMC article.
Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity.
Rošić S, Amouroux R, Requena CE, Gomes A, Emperle M, Beltran T, Rane JK, Linnett S, Selkirk ME, Schiffer PH, Bancroft AJ, Grencis RK, Jeltsch A, Hajkova P, Sarkies P. Rošić S, et al. Among authors: requena ce. Nat Genet. 2018 Mar;50(3):452-459. doi: 10.1038/s41588-018-0061-8. Epub 2018 Feb 19. Nat Genet. 2018. PMID: 29459678 Free PMC article.
Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS.
Stewart-Morgan KR, Requena CE, Flury V, Du Q, Heckhausen Z, Hajkova P, Groth A. Stewart-Morgan KR, et al. Among authors: requena ce. Nat Cell Biol. 2023 Jan;25(1):183-193. doi: 10.1038/s41556-022-01048-x. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635504 Free PMC article.
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