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Evaluation of a clinical pharmacogenetics model to predict methotrexate response in patients with rheumatoid arthritis.
López-Rodríguez R, Ferreiro-Iglesias A, Lima A, Bernardes M, Pawlik A, Paradowska-Gorycka A, Świerkot J, Slezak R, Gonzalez-Alvaro I, Narvaez J, Pérez-Pampín E, Mera-Varela A, Vidal-Bralo L, Acuña-Ochoa JG, Conde C, Gonzalez A. López-Rodríguez R, et al. Pharmacogenomics J. 2018 Jul;18(4):539-545. doi: 10.1038/s41397-018-0017-5. Epub 2018 Mar 8. Pharmacogenomics J. 2018. PMID: 29520081
Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.
Dieguez-Gonzalez R, Akar S, Calaza M, Perez-Pampin E, Costas J, Torres M, Vicario JL, Velloso ML, Navarro F, Narvaez J, Joven B, Herrero-Beaumont G, Gonzalez-Alvaro I, Fernandez-Gutierrez B, de la Serna AR, Carreño L, Lopez-Longo J, Caliz R, Collado-Escobar MD, Blanco FJ, Fernandez-Lopez C, Balsa A, Pascual-Salcedo D, Gomez-Reino JJ, Gonzalez A. Dieguez-Gonzalez R, et al. Ann Rheum Dis. 2009 Apr;68(4):579-83. doi: 10.1136/ard.2007.087304. Epub 2008 Apr 23. Ann Rheum Dis. 2009. PMID: 18434448
Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort.
González-Alvaro I, Descalzo MA, Carmona L; Estudio de la Morbilidad y Expresión Clínica de la Artritis Reumatoide Study Group. González-Alvaro I, et al. Arthritis Res Ther. 2008;10(6):R138. doi: 10.1186/ar2561. Epub 2008 Nov 26. Arthritis Res Ther. 2008. PMID: 19036152 Free PMC article.
Lack of association with rheumatoid arthritis of selected polymorphisms in 4 candidate genes: CFH, CD209, eotaxin-3, and MHC2TA.
Dieguez-Gonzalez R, Akar S, Calaza M, Gonzalez-Alvaro I, Fernandez-Gutierrez B, Lamas JR, de la Serna AR, Caliz R, Blanco FJ, Pascual-Salcedo D, Velloso ML, Perez-Pampin E, Pablos JL, Navarro F, Narvaez J, Lopez-Longo FJ, Herrero-Beaumont G, Gomez-Reino JJ, Gonzalez A. Dieguez-Gonzalez R, et al. J Rheumatol. 2009 Aug;36(8):1590-5. doi: 10.3899/jrheum.090022. Epub 2009 Jun 30. J Rheumatol. 2009. PMID: 19567623
Interleukin 15 levels in serum may predict a severe disease course in patients with early arthritis.
González-Álvaro I, Ortiz AM, Alvaro-Gracia JM, Castañeda S, Díaz-Sánchez B, Carvajal I, García-Vadillo JA, Humbría A, López-Bote JP, Patiño E, Tomero EG, Vicente EF, Sabando P, García-Vicuña R. González-Álvaro I, et al. PLoS One. 2011;6(12):e29492. doi: 10.1371/journal.pone.0029492. Epub 2011 Dec 29. PLoS One. 2011. PMID: 22242124 Free PMC article.
GWAS replication study confirms the association of PDE3A-SLCO1C1 with anti-TNF therapy response in rheumatoid arthritis.
Acosta-Colman I, Palau N, Tornero J, Fernández-Nebro A, Blanco F, González-Alvaro I, Cañete JD, Maymó J, Ballina J, Fernández-Gutiérrez B, Olivé A, Corominas H, Erra A, Canela-Xandri O, Alonso A, López Lasanta M, Tortosa R, Julià A, Marsal S. Acosta-Colman I, et al. Pharmacogenomics. 2013 May;14(7):727-34. doi: 10.2217/pgs.13.60. Pharmacogenomics. 2013. PMID: 23651021
194 results