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Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.
Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Danussi C, et al. Among authors: creighton cj. Nat Commun. 2018 Mar 13;9(1):1057. doi: 10.1038/s41467-018-03476-6. Nat Commun. 2018. PMID: 29535300 Free PMC article.
Functional annotation of rare gene aberration drivers of pancreatic cancer.
Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, Bertino JR, Gingras MC, Ittmann M, Kerrigan J, Chen K, Creighton CJ, Eterovic K, Mills GB, Scott KL. Tsang YH, et al. Among authors: creighton cj. Nat Commun. 2016 Jan 25;7:10500. doi: 10.1038/ncomms10500. Nat Commun. 2016. PMID: 26806015 Free PMC article.
Identification of diverse astrocyte populations and their malignant analogs.
John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, Creighton CJ, Deneen B. John Lin CC, et al. Among authors: creighton cj. Nat Neurosci. 2017 Mar;20(3):396-405. doi: 10.1038/nn.4493. Epub 2017 Feb 6. Nat Neurosci. 2017. PMID: 28166219 Free PMC article.
Pan-urologic cancer genomic subtypes that transcend tissue of origin.
Chen F, Zhang Y, Bossé D, Lalani AA, Hakimi AA, Hsieh JJ, Choueiri TK, Gibbons DL, Ittmann M, Creighton CJ. Chen F, et al. Among authors: creighton cj. Nat Commun. 2017 Aug 4;8(1):199. doi: 10.1038/s41467-017-00289-x. Nat Commun. 2017. PMID: 28775315 Free PMC article.
Daam2 driven degradation of VHL promotes gliomagenesis.
Zhu W, Krishna S, Garcia C, Lin CJ, Mitchell BD, Scott KL, Mohila CA, Creighton CJ, Yoo SH, Lee HK, Deneen B. Zhu W, et al. Among authors: creighton cj. Elife. 2017 Oct 20;6:e31926. doi: 10.7554/eLife.31926. Elife. 2017. PMID: 29053101 Free PMC article.
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.
Grzeskowiak CL, Kundu ST, Mo X, Ivanov AA, Zagorodna O, Lu H, Chapple RH, Tsang YH, Moreno D, Mosqueda M, Eterovic K, Fradette JJ, Ahmad S, Chen F, Chong Z, Chen K, Creighton CJ, Fu H, Mills GB, Gibbons DL, Scott KL. Grzeskowiak CL, et al. Among authors: creighton cj. Nat Commun. 2018 Jul 16;9(1):2732. doi: 10.1038/s41467-018-04572-3. Nat Commun. 2018. PMID: 30013058 Free PMC article.
468 results