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The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.
Fedoseienko A, Wijers M, Wolters JC, Dekker D, Smit M, Huijkman N, Kloosterhuis N, Klug H, Schepers A, Willems van Dijk K, Levels JHM, Billadeau DD, Hofker MH, van Deursen J, Westerterp M, Burstein E, Kuivenhoven JA, van de Sluis B. Fedoseienko A, et al. Among authors: van deursen j, van de sluis b. Circ Res. 2018 Jun 8;122(12):1648-1660. doi: 10.1161/CIRCRESAHA.117.312004. Epub 2018 Mar 15. Circ Res. 2018. PMID: 29545368
Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity.
Muller PA, van de Sluis B, Groot AJ, Verbeek D, Vonk WI, Maine GN, Burstein E, Wijmenga C, Vooijs M, Reits E, Klomp LW. Muller PA, et al. Among authors: van de sluis b. Traffic. 2009 May;10(5):514-27. doi: 10.1111/j.1600-0854.2009.00892.x. Epub 2009 Feb 11. Traffic. 2009. PMID: 19220812 Free article.
COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion.
van de Sluis B, Mao X, Zhai Y, Groot AJ, Vermeulen JF, van der Wall E, van Diest PJ, Hofker MH, Wijmenga C, Klomp LW, Cho KR, Fearon ER, Vooijs M, Burstein E. van de Sluis B, et al. Among authors: van der wall e, van diest pj. J Clin Invest. 2010 Jun;120(6):2119-30. doi: 10.1172/JCI40583. Epub 2010 May 10. J Clin Invest. 2010. PMID: 20458141 Free PMC article.
Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation.
Vonk WI, Bartuzi P, de Bie P, Kloosterhuis N, Wichers CG, Berger R, Haywood S, Klomp LW, Wijmenga C, van de Sluis B. Vonk WI, et al. Among authors: de bie p, van de sluis b. PLoS One. 2011;6(12):e29183. doi: 10.1371/journal.pone.0029183. Epub 2011 Dec 22. PLoS One. 2011. PMID: 22216203 Free PMC article.
Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model.
Aparicio-Vergara M, Hommelberg PP, Schreurs M, Gruben N, Stienstra R, Shiri-Sverdlov R, Kloosterhuis NJ, de Bruin A, van de Sluis B, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: van de sluis b, de bruin a. Hepatology. 2013 Feb;57(2):566-76. doi: 10.1002/hep.26046. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22941955
Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation.
Wijshake T, Malureanu LA, Baker DJ, Jeganathan KB, van de Sluis B, van Deursen JM. Wijshake T, et al. Among authors: van deursen jm, van de sluis b. PLoS Genet. 2012;8(12):e1003138. doi: 10.1371/journal.pgen.1003138. Epub 2012 Dec 27. PLoS Genet. 2012. PMID: 23300461 Free PMC article.
107 results