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Estrogen receptor α drives pro-resilient transcription in mouse models of depression.
Lorsch ZS, Loh YE, Purushothaman I, Walker DM, Parise EM, Salery M, Cahill ME, Hodes GE, Pfau ML, Kronman H, Hamilton PJ, Issler O, Labonté B, Symonds AE, Zucker M, Zhang TY, Meaney MJ, Russo SJ, Shen L, Bagot RC, Nestler EJ. Lorsch ZS, et al. Among authors: loh ye. Nat Commun. 2018 Mar 16;9(1):1116. doi: 10.1038/s41467-018-03567-4. Nat Commun. 2018. PMID: 29549264 Free PMC article.
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex.
Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, Montgomery SE, Loh YE, Labonté B, Conkey A, Symonds AE, Neve RL, Turecki G, Maze I, Dong Y, Zhang B, Shen L, Bagot RC, Nestler EJ. Lorsch ZS, et al. Among authors: loh ye. Nat Neurosci. 2019 Sep;22(9):1413-1423. doi: 10.1038/s41593-019-0462-8. Epub 2019 Aug 19. Nat Neurosci. 2019. PMID: 31427770 Free PMC article.
Sex-specific transcriptional signatures in human depression.
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ. Labonté B, et al. Among authors: loh ye. Nat Med. 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825715 Free PMC article.
Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain's Reward Circuitry.
Walker DM, Cates HM, Loh YE, Purushothaman I, Ramakrishnan A, Cahill KM, Lardner CK, Godino A, Kronman HG, Rabkin J, Lorsch ZS, Mews P, Doyle MA, Feng J, Labonté B, Koo JW, Bagot RC, Logan RW, Seney ML, Calipari ES, Shen L, Nestler EJ. Walker DM, et al. Among authors: loh ye. Biol Psychiatry. 2018 Dec 15;84(12):867-880. doi: 10.1016/j.biopsych.2018.04.009. Epub 2018 Apr 25. Biol Psychiatry. 2018. PMID: 29861096 Free PMC article.
Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior.
Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, Maze I. Lepack AE, et al. Among authors: loh ye. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12562-12567. doi: 10.1073/pnas.1608270113. Epub 2016 Oct 18. Proc Natl Acad Sci U S A. 2016. PMID: 27791098 Free PMC article.
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2.
Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, Shen L, Mansuy I, Jeltsch A, Akbarian S, Nestler EJ. Engmann O, et al. Among authors: loh ye. Biol Psychiatry. 2017 Dec 1;82(11):794-805. doi: 10.1016/j.biopsych.2017.04.013. Epub 2017 May 5. Biol Psychiatry. 2017. PMID: 28577753 Free PMC article.
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression.
Issler O, van der Zee YY, Ramakrishnan A, Wang J, Tan C, Loh YE, Purushothaman I, Walker DM, Lorsch ZS, Hamilton PJ, Peña CJ, Flaherty E, Hartley BJ, Torres-Berrío A, Parise EM, Kronman H, Duffy JE, Estill MS, Calipari ES, Labonté B, Neve RL, Tamminga CA, Brennand KJ, Dong Y, Shen L, Nestler EJ. Issler O, et al. Among authors: loh ye. Neuron. 2020 Jun 17;106(6):912-926.e5. doi: 10.1016/j.neuron.2020.03.023. Epub 2020 Apr 17. Neuron. 2020. PMID: 32304628 Free PMC article.
37 results