Sim BKL - Search Results

1

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA. Kisalu NK, et al. Among authors: sim bkl. Nat Med. 2018 May;24(4):408-416. doi: 10.1038/nm.4512. Epub 2018 Mar 19. Nat Med. 2018. PMID: 29554083 Free PMC article.

2

Cultivation of the exoerythrocytic stage of Plasmodium berghei in primary cultures of mouse hepatocytes and continuous mouse cell lines.

Long GW, Leath S, Schuman R, Hollingdale MR, Ballou WR, Sim BK, Hoffman SL. Long GW, et al. In Vitro Cell Dev Biol. 1989 Sep;25(9):857-62. doi: 10.1007/BF02623670. In Vitro Cell Dev Biol. 1989. PMID: 2676959

3

Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acids.

Narum DL, Haynes JD, Fuhrmann S, Moch K, Liang H, Hoffman SL, Sim BK. Narum DL, et al. Infect Immun. 2000 Apr;68(4):1964-6. doi: 10.1128/IAI.68.4.1964-1966.2000. Infect Immun. 2000. PMID: 10722589 Free PMC article.

4

Induction of biologically active antibodies in mice, rabbits, and monkeys by Plasmodium falciparum EBA-175 region II DNA vaccine.

Sim BK, Narum DL, Liang H, Fuhrmann SR, Obaldia N 3rd, Gramzinski R, Aguiar J, Haynes JD, Moch JK, Hoffman SL. Sim BK, et al. Mol Med. 2001 Apr;7(4):247-54. Mol Med. 2001. PMID: 11471569 Free PMC article.

5

Codon optimization of gene fragments encoding Plasmodium falciparum merzoite proteins enhances DNA vaccine protein expression and immunogenicity in mice.

Narum DL, Kumar S, Rogers WO, Fuhrmann SR, Liang H, Oakley M, Taye A, Sim BK, Hoffman SL. Narum DL, et al. Infect Immun. 2001 Dec;69(12):7250-3. doi: 10.1128/IAI.69.12.7250-7253.2001. Infect Immun. 2001. PMID: 11705894 Free PMC article.

6

Absence of antigenic competition in Aotus monkeys immunized with Plasmodium falciparum DNA vaccines delivered as a mixture.

Jones TR, Gramzinski RA, Aguiar JC, Sim BK, Narum DL, Fuhrmann SR, Kumar S, Obaldia N, Hoffman SL. Jones TR, et al. Vaccine. 2002 Feb 22;20(11-12):1675-80. doi: 10.1016/s0264-410x(01)00513-8. Vaccine. 2002. PMID: 11858878

7

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria.

Hoffman SL, Billingsley PF, James E, Richman A, Loyevsky M, Li T, Chakravarty S, Gunasekera A, Chattopadhyay R, Li M, Stafford R, Ahumada A, Epstein JE, Sedegah M, Reyes S, Richie TL, Lyke KE, Edelman R, Laurens MB, Plowe CV, Sim BK. Hoffman SL, et al. Hum Vaccin. 2010 Jan;6(1):97-106. doi: 10.4161/hv.6.1.10396. Epub 2010 Jan 21. Hum Vaccin. 2010. PMID: 19946222 Review.

8

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial.

Lyke KE, Laurens M, Adams M, Billingsley PF, Richman A, Loyevsky M, Chakravarty S, Plowe CV, Sim BK, Edelman R, Hoffman SL. Lyke KE, et al. PLoS One. 2010 Oct 21;5(10):e13490. doi: 10.1371/journal.pone.0013490. PLoS One. 2010. PMID: 21042404 Free PMC article. Clinical Trial.

9

Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies.

Sim BK, Narum DL, Chattopadhyay R, Ahumada A, Haynes JD, Fuhrmann SR, Wingard JN, Liang H, Moch JK, Hoffman SL. Sim BK, et al. PLoS One. 2011 Apr 14;6(4):e18393. doi: 10.1371/journal.pone.0018393. PLoS One. 2011. PMID: 21533224 Free PMC article.

10

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue.

Adjalley SH, Johnston GL, Li T, Eastman RT, Ekland EH, Eappen AG, Richman A, Sim BK, Lee MC, Hoffman SL, Fidock DA. Adjalley SH, et al. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):E1214-23. doi: 10.1073/pnas.1112037108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042867 Free PMC article.

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