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Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression.
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine TH, Manier S, Mishima Y, Murakami N, Bustoros M, Pistofidis RS, Reidy M, Shen YJ, Rahmat M, Lukyanchykov P, Karreci ES, Tsukamoto S, Shi J, Takagi S, Huynh D, Sacco A, Tai YT, Chesi M, Bergsagel PL, Roccaro AM, Azzi J, Ghobrial IM. Kawano Y, et al. Among authors: shen yj. J Clin Invest. 2018 Jun 1;128(6):2487-2499. doi: 10.1172/JCI88169. Epub 2018 May 14. J Clin Invest. 2018. PMID: 29558366 Free PMC article.
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.
Manier S, Huynh D, Shen YJ, Zhou J, Yusufzai T, Salem KZ, Ebright RY, Shi J, Park J, Glavey SV, Devine WG, Liu CJ, Leleu X, Quesnel B, Roche-Lestienne C, Snyder JK, Brown LE, Gray N, Bradner J, Whitesell L, Porco JA Jr, Ghobrial IM. Manier S, et al. Among authors: shen yj. Sci Transl Med. 2017 May 10;9(389):eaal2668. doi: 10.1126/scitranslmed.aal2668. Sci Transl Med. 2017. PMID: 28490664 Free PMC article.
Genome instability in multiple myeloma.
Neuse CJ, Lomas OC, Schliemann C, Shen YJ, Manier S, Bustoros M, Ghobrial IM. Neuse CJ, et al. Among authors: shen yj. Leukemia. 2020 Nov;34(11):2887-2897. doi: 10.1038/s41375-020-0921-y. Epub 2020 Jul 10. Leukemia. 2020. PMID: 32651540 Review.
Progression signature underlies clonal evolution and dissemination of multiple myeloma.
Shen YJ, Mishima Y, Shi J, Sklavenitis-Pistofidis R, Redd RA, Moschetta M, Manier S, Roccaro AM, Sacco A, Tai YT, Mercier F, Kawano Y, Su NK, Berrios B, Doench JG, Root DE, Michor F, Scadden DT, Ghobrial IM. Shen YJ, et al. Blood. 2021 Apr 29;137(17):2360-2372. doi: 10.1182/blood.2020005885. Blood. 2021. PMID: 33150374 Free PMC article.
Inhibition of MICA and MICB shedding enhances memory-like NK-cell-mediated cytotoxicity against multiple myeloma.
Tahri S, Piccinelli S, Su NK, Lampe L, Dong H, Vergara Cadavid J, Boiarsky R, Papazian N, Lightbody ED, Cao A, Alberge JB, Ferrari de Andrade L, Rahmat M, Shen Y, Blanco Fernández L, Zabaleta A, Günther A, Getz G, Sonneveld P, Cupedo T, Wucherpfennig KW, Ghobrial IM, Romee R. Tahri S, et al. Blood Adv. 2024 Oct 22;8(20):5365-5370. doi: 10.1182/bloodadvances.2023010869. Blood Adv. 2024. PMID: 39106432 Free PMC article. No abstract available.
479 results