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Redefining the ancestral origins of the interleukin-1 superfamily.
Rivers-Auty J, Daniels MJD, Colliver I, Robertson DL, Brough D. Rivers-Auty J, et al. Among authors: brough d. Nat Commun. 2018 Mar 20;9(1):1156. doi: 10.1038/s41467-018-03362-1. Nat Commun. 2018. PMID: 29559685 Free PMC article.
Regulation of interleukin-1 in acute brain injury.
Brough D, Tyrrell PJ, Allan SM. Brough D, et al. Trends Pharmacol Sci. 2011 Oct;32(10):617-22. doi: 10.1016/j.tips.2011.06.002. Epub 2011 Jul 23. Trends Pharmacol Sci. 2011. PMID: 21788085 Review.
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.
Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P. Martín-Sánchez F, et al. Among authors: brough d. Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868913 Free PMC article.
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Among authors: brough d. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.
P2X7 receptor-dependent tuning of gut epithelial responses to infection.
Huang SW, Walker C, Pennock J, Else K, Muller W, Daniels MJ, Pellegrini C, Brough D, Lopez-Castejon G, Cruickshank SM. Huang SW, et al. Among authors: brough d. Immunol Cell Biol. 2017 Feb;95(2):178-188. doi: 10.1038/icb.2016.75. Epub 2016 Aug 25. Immunol Cell Biol. 2017. PMID: 27559003 Free PMC article.
Inflammasomes as therapeutic targets for Alzheimer's disease.
White CS, Lawrence CB, Brough D, Rivers-Auty J. White CS, et al. Among authors: brough d. Brain Pathol. 2017 Mar;27(2):223-234. doi: 10.1111/bpa.12478. Brain Pathol. 2017. PMID: 28009077 Free PMC article. Review.
234 results