Hayden MR - Search Results

1

Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli.

Ladha S, Qiu X, Casal L, Caron NS, Ehrnhoefer DE, Hayden MR. Ladha S, et al. Among authors: hayden mr. Cell Death Discov. 2018 Mar 12;4:40. doi: 10.1038/s41420-018-0043-8. eCollection 2018. Cell Death Discov. 2018. PMID: 29560279 Free PMC article.

2

Mouse models of Huntington disease: variations on a theme.

Ehrnhoefer DE, Butland SL, Pouladi MA, Hayden MR. Ehrnhoefer DE, et al. Among authors: hayden mr. Dis Model Mech. 2009 Mar-Apr;2(3-4):123-9. doi: 10.1242/dmm.002451. Dis Model Mech. 2009. PMID: 19259385 Free PMC article.

3

Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression.

Pouladi MA, Xie Y, Skotte NH, Ehrnhoefer DE, Graham RK, Kim JE, Bissada N, Yang XW, Paganetti P, Friedlander RM, Leavitt BR, Hayden MR. Pouladi MA, et al. Among authors: hayden mr. Hum Mol Genet. 2010 Apr 15;19(8):1528-38. doi: 10.1093/hmg/ddq026. Epub 2010 Jan 22. Hum Mol Genet. 2010. PMID: 20097678 Free PMC article.

4

Small changes, big impact: posttranslational modifications and function of huntingtin in Huntington disease.

Ehrnhoefer DE, Sutton L, Hayden MR. Ehrnhoefer DE, et al. Among authors: hayden mr. Neuroscientist. 2011 Oct;17(5):475-92. doi: 10.1177/1073858410390378. Epub 2011 Feb 10. Neuroscientist. 2011. PMID: 21311053 Free PMC article. Review.

5

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

Carroll JB, Southwell AL, Graham RK, Lerch JP, Ehrnhoefer DE, Cao LP, Zhang WN, Deng Y, Bissada N, Henkelman RM, Hayden MR. Carroll JB, et al. Among authors: hayden mr. Mol Neurodegener. 2011 Aug 19;6:59. doi: 10.1186/1750-1326-6-59. Mol Neurodegener. 2011. PMID: 21854568 Free PMC article.

6

Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development.

Ehrnhoefer DE, Wong BK, Hayden MR. Ehrnhoefer DE, et al. Among authors: hayden mr. Nat Rev Drug Discov. 2011 Oct 21;10(11):853-67. doi: 10.1038/nrd3556. Nat Rev Drug Discov. 2011. PMID: 22015920 Free PMC article. Review.

7

Caspase-6 and neurodegeneration.

Graham RK, Ehrnhoefer DE, Hayden MR. Graham RK, et al. Among authors: hayden mr. Trends Neurosci. 2011 Dec;34(12):646-56. doi: 10.1016/j.tins.2011.09.001. Epub 2011 Oct 22. Trends Neurosci. 2011. PMID: 22018804 Review.

8

A quantitative method for the specific assessment of caspase-6 activity in cell culture.

Ehrnhoefer DE, Skotte NH, Savill J, Nguyen YT, Ladha S, Cao LP, Dullaghan E, Hayden MR. Ehrnhoefer DE, et al. Among authors: hayden mr. PLoS One. 2011;6(11):e27680. doi: 10.1371/journal.pone.0027680. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140457 Free PMC article.

9

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice.

Uribe V, Wong BK, Graham RK, Cusack CL, Skotte NH, Pouladi MA, Xie Y, Feinberg K, Ou Y, Ouyang Y, Deng Y, Franciosi S, Bissada N, Spreeuw A, Zhang W, Ehrnhoefer DE, Vaid K, Miller FD, Deshmukh M, Howland D, Hayden MR. Uribe V, et al. Among authors: hayden mr. Hum Mol Genet. 2012 May 1;21(9):1954-67. doi: 10.1093/hmg/dds005. Epub 2012 Jan 18. Hum Mol Genet. 2012. PMID: 22262731 Free PMC article.

10

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.

Pouladi MA, Brillaud E, Xie Y, Conforti P, Graham RK, Ehrnhoefer DE, Franciosi S, Zhang W, Poucheret P, Compte E, Maurel JC, Zuccato C, Cattaneo E, Néri C, Hayden MR. Pouladi MA, et al. Among authors: hayden mr. Neurobiol Dis. 2012 Dec;48(3):282-9. doi: 10.1016/j.nbd.2012.06.026. Epub 2012 Jul 10. Neurobiol Dis. 2012. PMID: 22796360

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