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Page 1
Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.
Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM. Zomerman WW, et al. Among authors: bruggeman swm. Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089. Cell Rep. 2018. PMID: 29562177 Free article.
CREB signaling activity correlates with differentiation and survival in medulloblastoma.
Armandari I, Zomerman WW, Plasschaert SLA, Smit MJ, Martini TEI, de Camargo Magalhães ES, Hogeling SM, Rozema-Huizinga GC, Lourens HJ, Meeuwsen-de Boer TGJ, Scherpen FJG, de Bont ESJM, Bruggeman SWM. Armandari I, et al. Among authors: bruggeman swm. Sci Rep. 2021 Aug 9;11(1):16077. doi: 10.1038/s41598-021-95381-0. Sci Rep. 2021. PMID: 34373489 Free PMC article.
The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.
Smit MJ, Martini TEI, Armandari I, Bočkaj I, Zomerman WW, de Camargo Magalhães ES, Siragna Z, Meeuwsen TGJ, Scherpen FJG, Schoots MH, Ritsema M, den Dunnen WFA, Hoving EW, Paridaen JTML, de Haan G, Guryev V, Bruggeman SWM. Smit MJ, et al. Among authors: bruggeman swm. J Cell Sci. 2022 Jun 1;135(11):jeb258608. doi: 10.1242/jcs.258608. Epub 2022 Jun 8. J Cell Sci. 2022. PMID: 35535520 Free PMC article.
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.
Bočkaj I, Martini TEI, de Camargo Magalhães ES, Bakker PL, Meeuwsen-de Boer TGJ, Armandari I, Meuleman SL, Mondria MT, Stok C, Kok YP, Bakker B, Wardenaar R, Seiler J, Broekhuis MJC, van den Bos H, Spierings DCJ, Ringnalda FCA, Clevers H, Schüller U, van Vugt MATM, Foijer F, Bruggeman SWM. Bočkaj I, et al. Among authors: bruggeman swm. PLoS Genet. 2021 Nov 9;17(11):e1009868. doi: 10.1371/journal.pgen.1009868. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34752469 Free PMC article.
Heat shock factor 1 (HSF1-pSer326) predicts response to bortezomib-containing chemotherapy in pediatric AML: a COG report.
Hoff FW, van Dijk AD, Qiu Y, Ruvolo PP, Gerbing RB, Leonti AR, Jenkins GN, Gamis AS, Aplenc R, Kolb EA, Alonzo TA, Meshinchi S, de Bont ESJM, Bruggeman SWM, Kornblau SM, Horton TM. Hoff FW, et al. Among authors: bruggeman swm. Blood. 2021 Feb 25;137(8):1050-1060. doi: 10.1182/blood.2020005208. Blood. 2021. PMID: 32959058 Free PMC article. Clinical Trial.
Stem cells and cancer; the polycomb connection.
Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M. Valk-Lingbeek ME, et al. Cell. 2004 Aug 20;118(4):409-18. doi: 10.1016/j.cell.2004.08.005. Cell. 2004. PMID: 15315754 Free article. Review.
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