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Page 1
Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.
Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM. Zomerman WW, et al. Among authors: scherpen fj. Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089. Cell Rep. 2018. PMID: 29562177 Free article.
CREB signaling activity correlates with differentiation and survival in medulloblastoma.
Armandari I, Zomerman WW, Plasschaert SLA, Smit MJ, Martini TEI, de Camargo Magalhães ES, Hogeling SM, Rozema-Huizinga GC, Lourens HJ, Meeuwsen-de Boer TGJ, Scherpen FJG, de Bont ESJM, Bruggeman SWM. Armandari I, et al. Among authors: scherpen fjg. Sci Rep. 2021 Aug 9;11(1):16077. doi: 10.1038/s41598-021-95381-0. Sci Rep. 2021. PMID: 34373489 Free PMC article.
The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.
Smit MJ, Martini TEI, Armandari I, Bočkaj I, Zomerman WW, de Camargo Magalhães ES, Siragna Z, Meeuwsen TGJ, Scherpen FJG, Schoots MH, Ritsema M, den Dunnen WFA, Hoving EW, Paridaen JTML, de Haan G, Guryev V, Bruggeman SWM. Smit MJ, et al. Among authors: scherpen fjg. J Cell Sci. 2022 Jun 1;135(11):jeb258608. doi: 10.1242/jcs.258608. Epub 2022 Jun 8. J Cell Sci. 2022. PMID: 35535520 Free PMC article.
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
Sikkema AH, Diks SH, den Dunnen WF, ter Elst A, Scherpen FJ, Hoving EW, Ruijtenbeek R, Boender PJ, de Wijn R, Kamps WA, Peppelenbosch MP, de Bont ES. Sikkema AH, et al. Among authors: scherpen fj. Cancer Res. 2009 Jul 15;69(14):5987-95. doi: 10.1158/0008-5472.CAN-08-3660. Epub 2009 Jun 30. Cancer Res. 2009. PMID: 19567681
EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.
Sikkema AH, den Dunnen WF, Hulleman E, van Vuurden DG, Garcia-Manero G, Yang H, Scherpen FJ, Kampen KR, Hoving EW, Kamps WA, Diks SH, Peppelenbosch MP, de Bont ES. Sikkema AH, et al. Among authors: scherpen fj. Neuro Oncol. 2012 Sep;14(9):1125-35. doi: 10.1093/neuonc/nos130. Epub 2012 Jun 21. Neuro Oncol. 2012. PMID: 22723427 Free PMC article.
Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.
van der Sligte NE, Scherpen FJ, Meeuwsen-de Boer TG, Lourens HJ, Ter Elst A, Diks SH, Guryev V, Peppelenbosch MP, van Leeuwen FN, de Bont ES. van der Sligte NE, et al. Among authors: scherpen fj. Proteomics. 2015 Apr;15(7):1245-54. doi: 10.1002/pmic.201400286. Epub 2015 Jan 21. Proteomics. 2015. PMID: 25422122
28 results