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The protein histidine phosphatase LHPP is a tumour suppressor.
Hindupur SK, Colombi M, Fuhs SR, Matter MS, Guri Y, Adam K, Cornu M, Piscuoglio S, Ng CKY, Betz C, Liko D, Quagliata L, Moes S, Jenoe P, Terracciano LM, Heim MH, Hunter T, Hall MN. Hindupur SK, et al. Among authors: matter ms. Nature. 2018 Mar 29;555(7698):678-682. doi: 10.1038/nature26140. Epub 2018 Mar 21. Nature. 2018. PMID: 29562234 Free PMC article.
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients.
Quagliata L, Matter MS, Piscuoglio S, Arabi L, Ruiz C, Procino A, Kovac M, Moretti F, Makowska Z, Boldanova T, Andersen JB, Hämmerle M, Tornillo L, Heim MH, Diederichs S, Cillo C, Terracciano LM. Quagliata L, et al. Among authors: matter ms. Hepatology. 2014 Mar;59(3):911-23. doi: 10.1002/hep.26740. Epub 2014 Jan 28. Hepatology. 2014. PMID: 24114970 Free PMC article.
HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models.
Andreozzi M, Quintavalle C, Benz D, Quagliata L, Matter M, Calabrese D, Tosti N, Ruiz C, Trapani F, Tornillo L, Fusco A, Heim MH, Ng CK, Pallante P, Terracciano LM, Piscuoglio S. Andreozzi M, et al. Neoplasia. 2016 Dec;18(12):724-731. doi: 10.1016/j.neo.2016.10.002. Epub 2016 Nov 14. Neoplasia. 2016. PMID: 27855356 Free PMC article.
Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes.
Burmeister K, Quagliata L, Andreozzi M, Eppenberger-Castori S, Matter MS, Perrina V, Grobholz R, Jochum W, Horber D, Moosmann P, Lehmann F, Köberle D, Ng CK, Piscuoglio S, Tornillo L, Terracciano LM. Burmeister K, et al. Among authors: matter ms. PLoS One. 2017 Apr 12;12(4):e0175563. doi: 10.1371/journal.pone.0175563. eCollection 2017. PLoS One. 2017. PMID: 28403223 Free PMC article.
High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models.
Quagliata L, Quintavalle C, Lanzafame M, Matter MS, Novello C, di Tommaso L, Pressiani T, Rimassa L, Tornillo L, Roncalli M, Cillo C, Pallante P, Piscuoglio S, Ng CK, Terracciano LM. Quagliata L, et al. Among authors: matter ms. Lab Invest. 2018 Jan;98(1):95-105. doi: 10.1038/labinvest.2017.107. Epub 2017 Oct 16. Lab Invest. 2018. PMID: 29035381 Free article.
Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib.
Quintavalle C, Hindupur SK, Quagliata L, Pallante P, Nigro C, Condorelli G, Andersen JB, Tagscherer KE, Roth W, Beguinot F, Heim MH, Ng CKY, Piscuoglio S, Matter MS. Quintavalle C, et al. Among authors: matter ms. Cell Death Dis. 2017 Oct 26;8(10):e3138. doi: 10.1038/cddis.2017.512. Cell Death Dis. 2017. PMID: 29072691 Free PMC article.
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