Qin S - Search Results

1

Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.

Zhang H, Zhou B, Qin S, Xu J, Harding R, Tempel W, Nayak V, Li Y, Loppnau P, Dou Y, Min J. Zhang H, et al. Among authors: qin s. Genes Dev. 2018 Mar 1;32(5-6):341-346. doi: 10.1101/gad.311639.118. Epub 2018 Mar 21. Genes Dev. 2018. PMID: 29563185 Free PMC article.

2

Structural basis for substrate recognition by the human N-terminal methyltransferase 1.

Dong C, Mao Y, Tempel W, Qin S, Li L, Loppnau P, Huang R, Min J. Dong C, et al. Among authors: qin s. Genes Dev. 2015 Nov 15;29(22):2343-8. doi: 10.1101/gad.270611.115. Epub 2015 Nov 5. Genes Dev. 2015. PMID: 26543161 Free PMC article.

3

Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.

Liu Y, Tempel W, Zhang Q, Liang X, Loppnau P, Qin S, Min J. Liu Y, et al. Among authors: qin s. J Biol Chem. 2016 Apr 22;291(17):9000-13. doi: 10.1074/jbc.M116.718973. Epub 2016 Mar 1. J Biol Chem. 2016. PMID: 26933034 Free PMC article.

4

Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.

Liu Y, Qin S, Lei M, Tempel W, Zhang Y, Loppnau P, Li Y, Min J. Liu Y, et al. Among authors: qin s. J Biol Chem. 2017 Apr 7;292(14):5655-5664. doi: 10.1074/jbc.M116.768374. Epub 2017 Feb 21. J Biol Chem. 2017. PMID: 28223359 Free PMC article.

5

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.

Liu Y, Qin S, Chen TY, Lei M, Dhar SS, Ho JC, Dong A, Loppnau P, Li Y, Lee MG, Min J. Liu Y, et al. Among authors: qin s. Nat Commun. 2019 Jan 3;10(1):36. doi: 10.1038/s41467-018-07906-3. Nat Commun. 2019. PMID: 30604749 Free PMC article.

6

Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.

Zhang M, Lei M, Qin S, Dong A, Yang A, Li Y, Loppnau P, Hughes TR, Min J, Liu Y. Zhang M, et al. Among authors: qin s. Biochim Biophys Acta Gene Regul Mech. 2021 Mar;1864(3):194688. doi: 10.1016/j.bbagrm.2021.194688. Epub 2021 Feb 6. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 33556623

7

Structure and function of the nucleosome-binding PWWP domain.

Qin S, Min J. Qin S, et al. Trends Biochem Sci. 2014 Nov;39(11):536-47. doi: 10.1016/j.tibs.2014.09.001. Epub 2014 Sep 29. Trends Biochem Sci. 2014. PMID: 25277115 Review.

8

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.

Jurkowska RZ, Qin S, Kungulovski G, Tempel W, Liu Y, Bashtrykov P, Stiefelmaier J, Jurkowski TP, Kudithipudi S, Weirich S, Tamas R, Wu H, Dombrovski L, Loppnau P, Reinhardt R, Min J, Jeltsch A. Jurkowska RZ, et al. Among authors: qin s. Nat Commun. 2017 Dec 12;8(1):2057. doi: 10.1038/s41467-017-02259-9. Nat Commun. 2017. PMID: 29234025 Free PMC article.

9

Structural Basis for the Binding Selectivity of Human CDY Chromodomains.

Dong C, Liu Y, Lyu TJ, Beldar S, Lamb KN, Tempel W, Li Y, Li Z, James LI, Qin S, Wang Y, Min J. Dong C, et al. Among authors: qin s. Cell Chem Biol. 2020 Jul 16;27(7):827-838.e7. doi: 10.1016/j.chembiol.2020.05.007. Epub 2020 May 28. Cell Chem Biol. 2020. PMID: 32470319 Free article.

10

Epigenetic targets and drug discovery: part 1: histone methylation.

Liu Y, Liu K, Qin S, Xu C, Min J. Liu Y, et al. Among authors: qin s. Pharmacol Ther. 2014 Sep;143(3):275-94. doi: 10.1016/j.pharmthera.2014.03.007. Epub 2014 Apr 2. Pharmacol Ther. 2014. PMID: 24704322 Review.

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