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Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3.
Akiyama Y, Kikuchi K, Saigusa D, Suzuki T, Takeuchi Y, Mishima E, Yamamoto Y, Ishida A, Sugawara D, Jinno D, Shima H, Toyohara T, Suzuki C, Souma T, Moriguchi T, Tomioka Y, Ito S, Abe T. Akiyama Y, et al. Among authors: saigusa d. PLoS One. 2013 Jul 9;8(7):e66518. doi: 10.1371/journal.pone.0066518. Print 2013. PLoS One. 2013. PMID: 23874392 Free PMC article.
Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.
Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: saigusa d. Tohoku J Exp Med. 2015 Jul;236(3):225-32. doi: 10.1620/tjem.236.225. Tohoku J Exp Med. 2015. PMID: 26118651 Free article.
A novel and sensitive assay for heme oxygenase activity.
Iwamori S, Sato E, Saigusa D, Yoshinari K, Ito S, Sato H, Takahashi N. Iwamori S, et al. Among authors: saigusa d. Am J Physiol Renal Physiol. 2015 Oct 1;309(7):F667-71. doi: 10.1152/ajprenal.00210.2015. Epub 2015 Jul 29. Am J Physiol Renal Physiol. 2015. PMID: 26224716 Free article.
Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, Maeda N, Karumanchi SA, Smithies O, Takahashi N. Li F, et al. Among authors: saigusa d. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13450-13455. doi: 10.1073/pnas.1614947113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821757 Free PMC article.
Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease.
Sato E, Mori T, Mishima E, Suzuki A, Sugawara S, Kurasawa N, Saigusa D, Miura D, Morikawa-Ichinose T, Saito R, Oba-Yabana I, Oe Y, Kisu K, Naganuma E, Koizumi K, Mokudai T, Niwano Y, Kudo T, Suzuki C, Takahashi N, Sato H, Abe T, Niwa T, Ito S. Sato E, et al. Among authors: saigusa d. Sci Rep. 2016 Nov 10;6:36618. doi: 10.1038/srep36618. Sci Rep. 2016. PMID: 27830716 Free PMC article.
A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways.
Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. Shima H, et al. Among authors: saigusa d. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. Sci Rep. 2017. PMID: 28507324 Free PMC article.
Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.
Matsuhashi T, Sato T, Kanno SI, Suzuki T, Matsuo A, Oba Y, Kikusato M, Ogasawara E, Kudo T, Suzuki K, Ohara O, Shimbo H, Nanto F, Yamaguchi H, Saigusa D, Mukaiyama Y, Watabe A, Kikuchi K, Shima H, Mishima E, Akiyama Y, Oikawa Y, Hsin-Jung HO, Akiyama Y, Suzuki C, Uematsu M, Ogata M, Kumagai N, Toyomizu M, Hozawa A, Mano N, Owada Y, Aiba S, Yanagisawa T, Tomioka Y, Kure S, Ito S, Nakada K, Hayashi KI, Osaka H, Abe T. Matsuhashi T, et al. Among authors: saigusa d. EBioMedicine. 2017 Jun;20:27-38. doi: 10.1016/j.ebiom.2017.05.016. Epub 2017 May 13. EBioMedicine. 2017. PMID: 28579242 Free PMC article.
133 results