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IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling.
Herjan T, Hong L, Bubenik J, Bulek K, Qian W, Liu C, Li X, Chen X, Yang H, Ouyang S, Zhou H, Zhao J, Vasu K, Cockman E, Aronica M, Asosingh K, Licatalosi DD, Qin J, Fox PL, Hamilton TA, Driscoll D, Li X. Herjan T, et al. Among authors: qian w. Nat Immunol. 2018 Apr;19(4):354-365. doi: 10.1038/s41590-018-0071-9. Epub 2018 Mar 21. Nat Immunol. 2018. PMID: 29563620 Free PMC article.
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.
Yao J, Kim TW, Qin J, Jiang Z, Qian Y, Xiao H, Lu Y, Qian W, Gulen MF, Sizemore N, DiDonato J, Sato S, Akira S, Su B, Li X. Yao J, et al. Among authors: qian w, qian y. J Biol Chem. 2007 Mar 2;282(9):6075-89. doi: 10.1074/jbc.M609039200. Epub 2006 Dec 29. J Biol Chem. 2007. PMID: 17197697 Free article.
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X. Liu C, et al. Among authors: qian w, qian y. Sci Signal. 2009 Oct 13;2(92):ra63. doi: 10.1126/scisignal.2000382. Sci Signal. 2009. PMID: 19825828 Free PMC article.
Crystal structure of IL-17 receptor B SEFIR domain.
Zhang B, Liu C, Qian W, Han Y, Li X, Deng J. Zhang B, et al. Among authors: qian w. J Immunol. 2013 Mar 1;190(5):2320-6. doi: 10.4049/jimmunol.1202922. Epub 2013 Jan 25. J Immunol. 2013. PMID: 23355738 Free PMC article.
HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization.
Herjan T, Yao P, Qian W, Li X, Liu C, Bulek K, Sun D, Yang WP, Zhu J, He A, Carman JA, Erzurum SC, Lipshitz HD, Fox PL, Hamilton TA, Li X. Herjan T, et al. Among authors: qian w. J Immunol. 2013 Jul 15;191(2):640-9. doi: 10.4049/jimmunol.1203315. Epub 2013 Jun 14. J Immunol. 2013. PMID: 23772036 Free PMC article.
4,189 results