Manning BD - Search Results

1

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H₂S Production.

Longchamp A, Mirabella T, Arduini A, MacArthur MR, Das A, Treviño-Villarreal JH, Hine C, Ben-Sahra I, Knudsen NH, Brace LE, Reynolds J, Mejia P, Tao M, Sharma G, Wang R, Corpataux JM, Haefliger JA, Ahn KH, Lee CH, Manning BD, Sinclair DA, Chen CS, Ozaki CK, Mitchell JR. Longchamp A, et al. Among authors: manning bd. Cell. 2018 Mar 22;173(1):117-129.e14. doi: 10.1016/j.cell.2018.03.001. Cell. 2018. PMID: 29570992 Free PMC article.

2

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S, Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, Manning BD. Düvel K, et al. Among authors: manning bd. Mol Cell. 2010 Jul 30;39(2):171-83. doi: 10.1016/j.molcel.2010.06.022. Mol Cell. 2010. PMID: 20670887 Free PMC article.

3

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD. Yecies JL, et al. Among authors: manning bd. Cell Metab. 2011 Jul 6;14(1):21-32. doi: 10.1016/j.cmet.2011.06.002. Cell Metab. 2011. PMID: 21723501 Free PMC article.

4

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

Ben-Sahra I, Howell JJ, Asara JM, Manning BD. Ben-Sahra I, et al. Among authors: manning bd. Science. 2013 Mar 15;339(6125):1323-8. doi: 10.1126/science.1228792. Epub 2013 Feb 21. Science. 2013. PMID: 23429703 Free PMC article.

5

A growing role for mTOR in promoting anabolic metabolism.

Howell JJ, Ricoult SJ, Ben-Sahra I, Manning BD. Howell JJ, et al. Among authors: manning bd. Biochem Soc Trans. 2013 Aug;41(4):906-12. doi: 10.1042/BST20130041. Biochem Soc Trans. 2013. PMID: 23863154 Review.

6

The TSC-mTOR pathway regulates macrophage polarization.

Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Among authors: manning bd. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.

7

Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response.

Lall R, Ganapathy S, Yang M, Xiao S, Xu T, Su H, Shadfan M, Asara JM, Ha CS, Ben-Sahra I, Manning BD, Little JB, Yuan ZM. Lall R, et al. Among authors: manning bd. Cell Death Differ. 2014 May;21(5):836-44. doi: 10.1038/cdd.2014.24. Epub 2014 Feb 28. Cell Death Differ. 2014. PMID: 24583639 Free PMC article.

8

The TSC complex is required for the benefits of dietary protein restriction on stress resistance in vivo.

Harputlugil E, Hine C, Vargas D, Robertson L, Manning BD, Mitchell JR. Harputlugil E, et al. Among authors: manning bd. Cell Rep. 2014 Aug 21;8(4):1160-70. doi: 10.1016/j.celrep.2014.07.018. Epub 2014 Aug 14. Cell Rep. 2014. PMID: 25131199 Free PMC article.

9

ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis.

Liu XS, Haines JE, Mehanna EK, Genet MD, Ben-Sahra I, Asara JM, Manning BD, Yuan ZM. Liu XS, et al. Among authors: manning bd. Genes Dev. 2014 Sep 1;28(17):1917-28. doi: 10.1101/gad.245910.114. Genes Dev. 2014. PMID: 25184678 Free PMC article.

10

Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP.

Ricoult SJ, Yecies JL, Ben-Sahra I, Manning BD. Ricoult SJ, et al. Among authors: manning bd. Oncogene. 2016 Mar 10;35(10):1250-60. doi: 10.1038/onc.2015.179. Epub 2015 Jun 1. Oncogene. 2016. PMID: 26028026 Free PMC article.

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