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Page 1
Ablation of the stress protease OMA1 protects against heart failure in mice.
Acin-Perez R, Lechuga-Vieco AV, Del Mar Muñoz M, Nieto-Arellano R, Torroja C, Sánchez-Cabo F, Jiménez C, González-Guerra A, Carrascoso I, Benincá C, Quiros PM, López-Otín C, Castellano JM, Ruíz-Cabello J, Jiménez-Borreguero LJ, Enríquez JA. Acin-Perez R, et al. Sci Transl Med. 2018 Mar 28;10(434):eaan4935. doi: 10.1126/scitranslmed.aan4935. Sci Transl Med. 2018. PMID: 29593106
Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.
Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Latorre-Pellicer A, et al. Nature. 2016 Jul 28;535(7613):561-5. doi: 10.1038/nature18618. Epub 2016 Jul 6. Nature. 2016. PMID: 27383793
Corrigendum: Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.
Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Latorre-Pellicer A, et al. Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature20773. Epub 2016 Dec 7. Nature. 2017. PMID: 27926738 No abstract available.
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, Sánchez-Díaz M, Díaz-García E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martínez-de-Mena R, Castejón-Vega B, Pun-García A, Través PG, Bonzón-Kulichenko E, García-Marqués F, Cussó L, A-González N, González-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzmán G, Larrazabal J, Herrero-Galán E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Muñoz-Cánoves P, Ibáñez B, Torres M, Ng LG, Priori SG, Bueno H, Vázquez J, Cordero MD, Bernal JA, Enríquez JA, Hidalgo A. Nicolás-Ávila JA, et al. Among authors: gonzalez guerra a. Cell. 2020 Oct 1;183(1):94-109.e23. doi: 10.1016/j.cell.2020.08.031. Epub 2020 Sep 15. Cell. 2020. PMID: 32937105 Free article.
Exosomes from eosinophils autoregulate and promote eosinophil functions.
Cañas JA, Sastre B, Mazzeo C, Fernández-Nieto M, Rodrigo-Muñoz JM, González-Guerra A, Izquierdo M, Barranco P, Quirce S, Sastre J, Del Pozo V. Cañas JA, et al. J Leukoc Biol. 2017 May;101(5):1191-1199. doi: 10.1189/jlb.3AB0516-233RR. Epub 2017 Jan 17. J Leukoc Biol. 2017. PMID: 28096299
The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval.
Tinaquero D, Crespo-García T, Utrilla RG, Nieto-Marín P, González-Guerra A, Rubio-Alarcón M, Cámara-Checa A, Dago M, Matamoros M, Pérez-Hernández M, Tamargo M, Cebrián J, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpón E; ITACA Investigators. Tinaquero D, et al. Sci Rep. 2020 Jul 1;10(1):10707. doi: 10.1038/s41598-020-67109-z. Sci Rep. 2020. PMID: 32612162 Free PMC article.
Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
Nieto-Marín P, Tinaquero D, Utrilla RG, Cebrián J, González-Guerra A, Crespo-García T, Cámara-Checa A, Rubio-Alarcón M, Dago M, Alfayate S, Filgueiras-Rama D, Peinado R, López-Sendón JL, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpón E; ITACA Consortium Investigators. Nieto-Marín P, et al. Among authors: gonzalez guerra a. Cardiovasc Res. 2022 Mar 16;118(4):1046-1060. doi: 10.1093/cvr/cvab045. Cardiovasc Res. 2022. PMID: 33576403
MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM).
García-Quintáns N, Sacristán S, Márquez-López C, Sánchez-Ramos C, Martinez-de-Benito F, Siniscalco D, González-Guerra A, Camafeita E, Roche-Molina M, Lytvyn M, Morera D, Guillen MI, Sanguino MA, Sanz-Rosa D, Martín-Pérez D, Garcia R, Bernal JA. García-Quintáns N, et al. Among authors: gonzalez guerra a. Nat Commun. 2023 Oct 13;14(1):6461. doi: 10.1038/s41467-023-41981-5. Nat Commun. 2023. PMID: 37833253 Free PMC article.
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