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Page 1
A licensing step links AID to transcription elongation for mutagenesis in B cells.
Methot SP, Litzler LC, Subramani PG, Eranki AK, Fifield H, Patenaude AM, Gilmore JC, Santiago GE, Bagci H, Côté JF, Larijani M, Verdun RE, Di Noia JM. Methot SP, et al. Among authors: fifield h. Nat Commun. 2018 Mar 28;9(1):1248. doi: 10.1038/s41467-018-03387-6. Nat Commun. 2018. PMID: 29593215 Free PMC article.
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Zahn A, Eranki AK, Patenaude AM, Methot SP, Fifield H, Cortizas EM, Foster P, Imai K, Durandy A, Larijani M, Verdun RE, Di Noia JM. Zahn A, et al. Among authors: fifield h. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E988-97. doi: 10.1073/pnas.1320486111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591601 Free PMC article.
Zebrafish AID is capable of deaminating methylated deoxycytidines.
Abdouni H, King JJ, Suliman M, Quinlan M, Fifield H, Larijani M. Abdouni H, et al. Among authors: fifield h. Nucleic Acids Res. 2013 May 1;41(10):5457-68. doi: 10.1093/nar/gkt212. Epub 2013 Apr 12. Nucleic Acids Res. 2013. PMID: 23585279 Free PMC article.
AID, APOBEC3A and APOBEC3B efficiently deaminate deoxycytidines neighboring DNA damage induced by oxidation or alkylation.
Diamond CP, Im J, Button EA, Huebert DNG, King JJ, Borzooee F, Abdouni HS, Bacque L, McCarthy E, Fifield H, Berghuis LM, Larijani M. Diamond CP, et al. Among authors: fifield h. Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129415. doi: 10.1016/j.bbagen.2019.129415. Epub 2019 Aug 9. Biochim Biophys Acta Gen Subj. 2019. PMID: 31404619
Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys.
Holland SJ, Berghuis LM, King JJ, Iyer LM, Sikora K, Fifield H, Peter S, Quinlan EM, Sugahara F, Shingate P, Trancoso I, Iwanami N, Temereva E, Strohmeier C, Kuratani S, Venkatesh B, Evanno G, Aravind L, Schorpp M, Larijani M, Boehm T. Holland SJ, et al. Among authors: fifield h. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3211-E3220. doi: 10.1073/pnas.1720871115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555777 Free PMC article.