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Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo.
Foquet L, Schafer C, Minkah NK, Alanine DGW, Flannery EL, Steel RWJ, Sack BK, Camargo N, Fishbaugher M, Betz W, Nguyen T, Billman ZP, Wilson EM, Bial J, Murphy SC, Draper SJ, Mikolajczak SA, Kappe SHI. Foquet L, et al. Among authors: nguyen t. Front Immunol. 2018 Mar 14;9:524. doi: 10.3389/fimmu.2018.00524. eCollection 2018. Front Immunol. 2018. PMID: 29593746 Free PMC article.
Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice.
Sack BK, Mikolajczak SA, Fishbaugher M, Vaughan AM, Flannery EL, Nguyen T, Betz W, Jane Navarro M, Foquet L, Steel RWJ, Billman ZP, Murphy SC, Hoffman SL, Chakravarty S, Sim BKL, Behet M, Reuling IJ, Walk J, Scholzen A, Sauerwein RW, Ishizuka AS, Flynn B, Seder RA, Kappe SHI. Sack BK, et al. Among authors: nguyen t. NPJ Vaccines. 2017 Oct 9;2:27. doi: 10.1038/s41541-017-0028-2. eCollection 2017. NPJ Vaccines. 2017. PMID: 29263882 Free PMC article.
Assessing drug efficacy against Plasmodium falciparum liver stages in vivo.
Flannery EL, Foquet L, Chuenchob V, Fishbaugher M, Billman Z, Navarro MJ, Betz W, Olsen TM, Lee J, Camargo N, Nguyen T, Schafer C, Sack BK, Wilson EM, Saunders J, Bial J, Campo B, Charman SA, Murphy SC, Phillips MA, Kappe SH, Mikolajczak SA. Flannery EL, et al. Among authors: nguyen t. JCI Insight. 2018 Jan 11;3(1):e92587. doi: 10.1172/jci.insight.92587. eCollection 2018 Jan 11. JCI Insight. 2018. PMID: 29321371 Free PMC article.
Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies.
Zenklusen I, Jongo S, Abdulla S, Ramadhani K, Lee Sim BK, Cardamone H, Flannery EL, Nguyen T, Fishbaugher M, Steel RWJ, Betz W, Carmago N, Mikolajczak S, Kappe SHI, Hoffman SL, Sack BK, Daubenberger C. Zenklusen I, et al. Among authors: nguyen t. J Infect Dis. 2018 Apr 23;217(10):1569-1578. doi: 10.1093/infdis/jiy080. J Infect Dis. 2018. PMID: 29438525 Free PMC article. Clinical Trial.
A replication-competent late liver stage-attenuated human malaria parasite.
Goswami D, Betz W, Locham NK, Parthiban C, Brager C, Schäfer C, Camargo N, Nguyen T, Kennedy SY, Murphy SC, Vaughan AM, Kappe SH. Goswami D, et al. Among authors: nguyen t. JCI Insight. 2020 Jul 9;5(13):e135589. doi: 10.1172/jci.insight.135589. JCI Insight. 2020. PMID: 32484795 Free PMC article.
Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP.
Steel RWJ, Vigdorovich V, Dambrauskas N, Wilder BK, Arredondo SA, Goswami D, Kumar S, Carbonetti S, Swearingen KE, Nguyen T, Betz W, Camargo N, Fisher BS, Soden J, Thomas H, Freeth J, Moritz RL, Noah Sather D, Kappe SHI. Steel RWJ, et al. Among authors: nguyen t. Sci Rep. 2021 May 31;11(1):11328. doi: 10.1038/s41598-021-90722-5. Sci Rep. 2021. PMID: 34059712 Free PMC article.
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