The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
Spagnol V, Oliveira CAB, Randle SJ, Passos PMS, Correia CRSTB, Simaroli NB, Oliveira JS, Mevissen TET, Medeiros AC, Gomes MD, Komander D, Laman H, Teixeira FR.
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Biochim Biophys Acta Gen Subj. 2021 Jan;1865(1):129754. doi: 10.1016/j.bbagen.2020.129754. Epub 2020 Sep 30.
Biochim Biophys Acta Gen Subj. 2021.
PMID: 33010352
Free PMC article.