Gelman IH - Search Results

1

Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361).

Smolinski MP, Bu Y, Clements J, Gelman IH, Hegab T, Cutler DL, Fang JWS, Fetterly G, Kwan R, Barnett A, Lau JYN, Hangauer DG. Smolinski MP, et al. Among authors: gelman ih. J Med Chem. 2018 Jun 14;61(11):4704-4719. doi: 10.1021/acs.jmedchem.8b00164. Epub 2018 Apr 17. J Med Chem. 2018. PMID: 29617135

2

SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition.

Su B, Zheng Q, Vaughan MM, Bu Y, Gelman IH. Su B, et al. Among authors: gelman ih. Cancer Res. 2006 Jun 1;66(11):5599-607. doi: 10.1158/0008-5472.CAN-05-4123. Cancer Res. 2006. PMID: 16740695

3

v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex.

Bu Y, Gelman IH. Bu Y, et al. Among authors: gelman ih. J Biol Chem. 2007 Sep 14;282(37):26725-26739. doi: 10.1074/jbc.M702885200. Epub 2007 Jul 10. J Biol Chem. 2007. PMID: 17626016 Free article.

4

Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro.

Lau GM, Lau GM, Yu GL, Gelman IH, Gutowski A, Hangauer D, Fang JW. Lau GM, et al. Among authors: gelman ih. Dig Dis Sci. 2009 Jul;54(7):1465-74. doi: 10.1007/s10620-008-0519-0. Epub 2008 Nov 1. Dig Dis Sci. 2009. PMID: 18979199

5

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.

Sachdev S, Bu Y, Gelman IH. Sachdev S, et al. Among authors: gelman ih. BMC Cancer. 2009 Jan 12;9:12. doi: 10.1186/1471-2407-9-12. BMC Cancer. 2009. PMID: 19138410 Free PMC article.

6

SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway.

Su B, Bu Y, Engelberg D, Gelman IH. Su B, et al. Among authors: gelman ih. J Biol Chem. 2010 Feb 12;285(7):4578-86. doi: 10.1074/jbc.M109.073494. Epub 2009 Dec 15. J Biol Chem. 2010. PMID: 20018890 Free PMC article.

7

Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src.

Bu Y, Gao L, Gelman IH. Bu Y, et al. Among authors: gelman ih. Int J Cancer. 2011 Apr 15;128(8):1836-42. doi: 10.1002/ijc.25524. Int J Cancer. 2011. PMID: 20568114 Free PMC article.

8

v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts.

Moissoglu K, Gelman IH. Moissoglu K, et al. Among authors: gelman ih. J Biol Chem. 2003 Nov 28;278(48):47946-59. doi: 10.1074/jbc.M302720200. Epub 2003 Sep 18. J Biol Chem. 2003. PMID: 14500722 Free article.

9

Focal adhesion kinase controls prostate cancer progression via intrinsic kinase and scaffolding functions.

Figel S, Gelman IH. Figel S, et al. Among authors: gelman ih. Anticancer Agents Med Chem. 2011 Sep;11(7):607-16. doi: 10.2174/187152011796817646. Anticancer Agents Med Chem. 2011. PMID: 21355844 Review.

10

Src-family tyrosine kinases as therapeutic targets in advanced cancer.

Gelman IH. Gelman IH. Front Biosci (Elite Ed). 2011 Jun 1;3(3):801-7. doi: 10.2741/e287. Front Biosci (Elite Ed). 2011. PMID: 21622091 Free article. Review.

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