Celik H - Search Results

1

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.

Jeong M, Park HJ, Celik H, Ostrander EL, Reyes JM, Guzman A, Rodriguez B, Lei Y, Lee Y, Ding L, Guryanova OA, Li W, Goodell MA, Challen GA. Jeong M, et al. Among authors: celik h. Cell Rep. 2018 Apr 3;23(1):1-10. doi: 10.1016/j.celrep.2018.03.025. Cell Rep. 2018. PMID: 29617651 Free PMC article.

2

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.

Challen GA, Sun D, Mayle A, Jeong M, Luo M, Rodriguez B, Mallaney C, Celik H, Yang L, Xia Z, Cullen S, Berg J, Zheng Y, Darlington GJ, Li W, Goodell MA. Challen GA, et al. Among authors: celik h. Cell Stem Cell. 2014 Sep 4;15(3):350-364. doi: 10.1016/j.stem.2014.06.018. Epub 2014 Aug 14. Cell Stem Cell. 2014. PMID: 25130491 Free PMC article.

3

Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation.

Celik H, Mallaney C, Kothari A, Ostrander EL, Eultgen E, Martens A, Miller CA, Hundal J, Klco JM, Challen GA. Celik H, et al. Blood. 2015 Jan 22;125(4):619-28. doi: 10.1182/blood-2014-08-594564. Blood. 2015. PMID: 25416276 Free PMC article.

4

DNA methylation in normal and malignant hematopoiesis.

Celik H, Kramer A, Challen GA. Celik H, et al. Int J Hematol. 2016 Jun;103(6):617-26. doi: 10.1007/s12185-016-1957-7. Epub 2016 Mar 4. Int J Hematol. 2016. PMID: 26943352 Review.

5

Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation.

McDonald JI, Celik H, Rois LE, Fishberger G, Fowler T, Rees R, Kramer A, Martens A, Edwards JR, Challen GA. McDonald JI, et al. Among authors: celik h. Biol Open. 2016 Jun 15;5(6):866-74. doi: 10.1242/bio.019067. Biol Open. 2016. PMID: 27170255 Free PMC article.

6

Dnmt3a regulates T-cell development and suppresses T-ALL transformation.

Kramer AC, Kothari A, Wilson WC, Celik H, Nikitas J, Mallaney C, Ostrander EL, Eultgen E, Martens A, Valentine MC, Young AL, Druley TE, Figueroa ME, Zhang B, Challen GA. Kramer AC, et al. Among authors: celik h. Leukemia. 2017 Nov;31(11):2479-2490. doi: 10.1038/leu.2017.89. Epub 2017 Mar 21. Leukemia. 2017. PMID: 28321121 Free PMC article.

7

JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells.

Celik H, Koh WK, Kramer AC, Ostrander EL, Mallaney C, Fisher DAC, Xiang J, Wilson WC, Martens A, Kothari A, Fishberger G, Tycksen E, Karpova D, Duncavage EJ, Lee Y, Oh ST, Challen GA. Celik H, et al. Cancer Cell. 2018 Nov 12;34(5):741-756.e8. doi: 10.1016/j.ccell.2018.10.008. Cancer Cell. 2018. PMID: 30423295 Free PMC article.

8

Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis.

Mallaney C, Ostrander EL, Celik H, Kramer AC, Martens A, Kothari A, Koh WK, Haussler E, Iwamori N, Gontarz P, Zhang B, Challen GA. Mallaney C, et al. Among authors: celik h. Leukemia. 2019 Oct;33(10):2506-2521. doi: 10.1038/s41375-019-0462-4. Epub 2019 Apr 1. Leukemia. 2019. PMID: 30936419 Free PMC article.

9

TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow.

Abou-Ezzi G, Supakorndej T, Zhang J, Anthony B, Krambs J, Celik H, Karpova D, Craft CS, Link DC. Abou-Ezzi G, et al. Among authors: celik h. Stem Cell Reports. 2019 Jul 9;13(1):48-60. doi: 10.1016/j.stemcr.2019.05.017. Epub 2019 Jun 13. Stem Cell Reports. 2019. PMID: 31204302 Free PMC article.

10

Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness.

Ostrander EL, Kramer AC, Mallaney C, Celik H, Koh WK, Fairchild J, Haussler E, Zhang CRC, Challen GA. Ostrander EL, et al. Among authors: celik h. Stem Cell Reports. 2020 Apr 14;14(4):551-560. doi: 10.1016/j.stemcr.2020.02.011. Epub 2020 Mar 26. Stem Cell Reports. 2020. PMID: 32220332 Free PMC article.

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