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Page 1
TMEM59 potentiates Wnt signaling by promoting signalosome formation.
Gerlach JP, Jordens I, Tauriello DVF, van 't Land-Kuper I, Bugter JM, Noordstra I, van der Kooij J, Low TY, Pimentel-Muiños FX, Xanthakis D, Fenderico N, Rabouille C, Heck AJR, Egan DA, Maurice MM. Gerlach JP, et al. Among authors: bugter jm. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3996-E4005. doi: 10.1073/pnas.1721321115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632210 Free PMC article.
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
Spit M, Fenderico N, Jordens I, Radaszkiewicz T, Lindeboom RG, Bugter JM, Cristobal A, Ootes L, van Osch M, Janssen E, Boonekamp KE, Hanakova K, Potesil D, Zdrahal Z, Boj SF, Medema JP, Bryja V, Koo BK, Vermeulen M, Maurice MM. Spit M, et al. Among authors: bugter jm. EMBO J. 2020 Sep 15;39(18):e103932. doi: 10.15252/embj.2019103932. Epub 2020 Aug 10. EMBO J. 2020. PMID: 32965059 Free PMC article.
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland M, Hartmann O, Tauch S, Bugter JM, Prieto-Garcia C, Schulte C, Loebbert S, Solvie D, Bitman-Lotan E, Narain A, Jacomin AC, Schuelein-Voelk C, Fuss CT, Pahor N, Ade C, Buck V, Potente M, Li V, Beliu G, Wiegering A, Grossmann T, Eilers M, Wolf E, Maric H, Rosenfeldt M, Maurice MM, Dikic I, Gallant P, Orian A, Diefenbacher ME. Reissland M, et al. Among authors: bugter jm. Oncogene. 2024 Dec;43(50):3645-3659. doi: 10.1038/s41388-024-03141-x. Epub 2024 Oct 23. Oncogene. 2024. PMID: 39443725 Free PMC article.