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Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Johnson CB, May BR, Riesenberg BP, Suriano S, Mehrotra S, Garrett-Mayer E, Salem ML, Jeng EK, Wong HC, Paulos CM, Wrangle JM, Cole DJ, Rubinstein MP. Johnson CB, et al. Among authors: mehrotra s. Cancer Res. 2018 Jun 1;78(11):3067-3074. doi: 10.1158/0008-5472.CAN-17-2153. Epub 2018 Apr 10. Cancer Res. 2018. PMID: 29636345 Free PMC article.
Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death.
Norell H, Martins da Palma T, Lesher A, Kaur N, Mehrotra M, Naga OS, Spivey N, Olafimihan S, Chakraborty NG, Voelkel-Johnson C, Nishimura MI, Mukherji B, Mehrotra S. Norell H, et al. Among authors: mehrotra m, mehrotra s. Cancer Res. 2009 Aug 1;69(15):6282-9. doi: 10.1158/0008-5472.CAN-09-1176. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638595 Free PMC article.
A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.
Mehrotra S, Al-Khami AA, Klarquist J, Husain S, Naga O, Eby JM, Murali AK, Lyons GE, Li M, Spivey ND, Norell H, Martins da Palma T, Onicescu G, Diaz-Montero CM, Garrett-Mayer E, Cole DJ, Le Poole IC, Nishimura MI. Mehrotra S, et al. J Immunol. 2012 Aug 15;189(4):1627-38. doi: 10.4049/jimmunol.1103271. Epub 2012 Jul 13. J Immunol. 2012. PMID: 22798675 Free PMC article.
Th17 cells in cancer: the ultimate identity crisis.
Bailey SR, Nelson MH, Himes RA, Li Z, Mehrotra S, Paulos CM. Bailey SR, et al. Among authors: mehrotra s. Front Immunol. 2014 Jun 17;5:276. doi: 10.3389/fimmu.2014.00276. eCollection 2014. Front Immunol. 2014. PMID: 24987392 Free PMC article. Review.
Promoting thiol expression increases the durability of antitumor T-cell functions.
Kesarwani P, Al-Khami AA, Scurti G, Thyagarajan K, Kaur N, Husain S, Fang Q, Naga OS, Simms P, Beeson G, Voelkel-Johnson C, Garrett-Mayer E, Beeson CC, Nishimura MI, Mehrotra S. Kesarwani P, et al. Among authors: mehrotra s. Cancer Res. 2014 Nov 1;74(21):6036-6047. doi: 10.1158/0008-5472.CAN-14-1084. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164014 Free PMC article.
The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. Nelson MH, et al. Among authors: mehrotra s. J Immunol. 2015 Feb 15;194(4):1737-47. doi: 10.4049/jimmunol.1401082. Epub 2015 Jan 9. J Immunol. 2015. PMID: 25576595 Free PMC article.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Rubinstein MP, et al. Among authors: mehrotra s. Cancer Immunol Immunother. 2015 May;64(5):539-49. doi: 10.1007/s00262-015-1655-y. Epub 2015 Feb 13. Cancer Immunol Immunother. 2015. PMID: 25676709 Free PMC article.
IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells.
Andrijauskaite K, Suriano S, Cloud CA, Li M, Kesarwani P, Stefanik LS, Moxley KM, Salem ML, Garrett-Mayer E, Paulos CM, Mehrotra S, Kochenderfer JN, Cole DJ, Rubinstein MP. Andrijauskaite K, et al. Among authors: mehrotra s. Cancer Gene Ther. 2015 Jul;22(7):360-7. doi: 10.1038/cgt.2015.28. Epub 2015 Jul 17. Cancer Gene Ther. 2015. PMID: 26182912 Free PMC article.
874 results