Lai Y - Search Results

1

Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction.

Mao Q, Lai Y, Wang J. Mao Q, et al. Among authors: lai y. Drug Metab Dispos. 2018 May;46(5):561-566. doi: 10.1124/dmd.118.081356. Drug Metab Dispos. 2018. PMID: 29636376 Free PMC article.

2

Structure-activity relationships for interaction with multidrug resistance protein 2 (ABCC2/MRP2): the role of torsion angle for a series of biphenyl-substituted heterocycles.

Lai Y, Xing L, Poda GI, Hu Y. Lai Y, et al. Drug Metab Dispos. 2007 Jun;35(6):937-45. doi: 10.1124/dmd.106.013250. Epub 2007 Mar 19. Drug Metab Dispos. 2007. PMID: 17371800

3

Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human.

Li M, Yuan H, Li N, Song G, Zheng Y, Baratta M, Hua F, Thurston A, Wang J, Lai Y. Li M, et al. Among authors: lai y. Eur J Pharm Sci. 2008 Sep 2;35(1-2):114-26. doi: 10.1016/j.ejps.2008.06.008. Epub 2008 Jun 28. Eur J Pharm Sci. 2008. PMID: 18639632

4

Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion.

Lai Y. Lai Y. Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1175-87. doi: 10.1517/17425250903127234. Expert Opin Drug Metab Toxicol. 2009. PMID: 19611403 Review.

5

Evaluation of drug transporter interactions in drug discovery and development.

Lai Y, Sampson KE, Stevens JC. Lai Y, et al. Comb Chem High Throughput Screen. 2010 Feb;13(2):112-34. doi: 10.2174/138620710790596772. Comb Chem High Throughput Screen. 2010. PMID: 20053160 Review.

6

Pharmacokinetic interaction of the antiparasitic agents ivermectin and spinosad in dogs.

Dunn ST, Hedges L, Sampson KE, Lai Y, Mahabir S, Balogh L, Locuson CW. Dunn ST, et al. Among authors: lai y. Drug Metab Dispos. 2011 May;39(5):789-95. doi: 10.1124/dmd.110.034827. Epub 2011 Feb 14. Drug Metab Dispos. 2011. PMID: 21321059

7

Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometry.

Deo AK, Prasad B, Balogh L, Lai Y, Unadkat JD. Deo AK, et al. Among authors: lai y. Drug Metab Dispos. 2012 May;40(5):852-5. doi: 10.1124/dmd.111.043810. Epub 2012 Feb 8. Drug Metab Dispos. 2012. PMID: 22318656 Free PMC article.

8

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS. Jones HM, et al. Among authors: lai y. Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16. Drug Metab Dispos. 2012. PMID: 22344703

9

In vitro evaluation of hepatic transporter-mediated clinical drug-drug interactions: hepatocyte model optimization and retrospective investigation.

Bi YA, Kimoto E, Sevidal S, Jones HM, Barton HA, Kempshall S, Whalen KM, Zhang H, Ji C, Fenner KS, El-Kattan AF, Lai Y. Bi YA, et al. Among authors: lai y. Drug Metab Dispos. 2012 Jun;40(6):1085-92. doi: 10.1124/dmd.111.043489. Epub 2012 Mar 1. Drug Metab Dispos. 2012. PMID: 22381335 Review.

10

Beyond the ITC White Paper: emerging sciences in drug transporters and opportunities for drug development.

Lai Y, Hsiao P. Lai Y, et al. Curr Pharm Des. 2014;20(10):1577-94. doi: 10.2174/13816128113199990467. Curr Pharm Des. 2014. PMID: 23789952 Review.

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