Cleary ML - Search Results

1

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing.

Schneidawind C, Jeong J, Schneidawind D, Kim IS, Duque-Afonso J, Wong SHK, Iwasaki M, Breese EH, Zehnder JL, Porteus M, Cleary ML. Schneidawind C, et al. Among authors: cleary ml. Blood Adv. 2018 Apr 24;2(8):832-845. doi: 10.1182/bloodadvances.2017013748. Blood Adv. 2018. PMID: 29650777 Free PMC article.

2

MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.

Buechele C, Breese EH, Schneidawind D, Lin CH, Jeong J, Duque-Afonso J, Wong SH, Smith KS, Negrin RS, Porteus M, Cleary ML. Buechele C, et al. Among authors: cleary ml. Blood. 2015 Oct 1;126(14):1683-94. doi: 10.1182/blood-2015-05-646398. Epub 2015 Aug 26. Blood. 2015. PMID: 26311362 Free PMC article.

3

Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.

Breese EH, Buechele C, Dawson C, Cleary ML, Porteus MH. Breese EH, et al. Among authors: cleary ml. PLoS One. 2015 Sep 9;10(9):e0136644. doi: 10.1371/journal.pone.0136644. eCollection 2015. PLoS One. 2015. PMID: 26351841 Free PMC article.

4

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.

Becker H, Greve G, Kataoka K, Mallm JP, Duque-Afonso J, Ma T, Niemöller C, Pantic M, Duyster J, Cleary ML, Schüler J, Rippe K, Ogawa S, Lübbert M. Becker H, et al. Among authors: cleary ml. Blood Adv. 2019 Mar 12;3(5):761-765. doi: 10.1182/bloodadvances.2018023879. Blood Adv. 2019. PMID: 30833276 Free PMC article.

5

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells.

Jeong J, Jager A, Domizi P, Pavel-Dinu M, Gojenola L, Iwasaki M, Wei MC, Pan F, Zehnder JL, Porteus MH, Davis KL, Cleary ML. Jeong J, et al. Among authors: cleary ml. Blood Adv. 2019 Oct 8;3(19):2825-2835. doi: 10.1182/bloodadvances.2019000450. Blood Adv. 2019. PMID: 31582391 Free PMC article.

6

Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML. Wong P, et al. Among authors: cleary ml. Genes Dev. 2007 Nov 1;21(21):2762-74. doi: 10.1101/gad.1602107. Epub 2007 Oct 17. Genes Dev. 2007. PMID: 17942707 Free PMC article.

7

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Somervaille TC, et al. Among authors: cleary ml. Cell Stem Cell. 2009 Feb 6;4(2):129-40. doi: 10.1016/j.stem.2008.11.015. Cell Stem Cell. 2009. PMID: 19200802 Free PMC article.

8

Epigenetic roles of MLL oncoproteins are dependent on NF-κB.

Kuo HP, Wang Z, Lee DF, Iwasaki M, Duque-Afonso J, Wong SH, Lin CH, Figueroa ME, Su J, Lemischka IR, Cleary ML. Kuo HP, et al. Among authors: cleary ml. Cancer Cell. 2013 Oct 14;24(4):423-37. doi: 10.1016/j.ccr.2013.08.019. Epub 2013 Sep 19. Cancer Cell. 2013. PMID: 24054986 Free PMC article.

9

The AML salad bowl.

Duque-Afonso J, Cleary ML. Duque-Afonso J, et al. Among authors: cleary ml. Cancer Cell. 2014 Mar 17;25(3):265-7. doi: 10.1016/j.ccr.2014.03.002. Cancer Cell. 2014. PMID: 24651007 Free PMC article.

10

The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.

Wong SH, Goode DL, Iwasaki M, Wei MC, Kuo HP, Zhu L, Schneidawind D, Duque-Afonso J, Weng Z, Cleary ML. Wong SH, et al. Among authors: cleary ml. Cancer Cell. 2015 Aug 10;28(2):198-209. doi: 10.1016/j.ccell.2015.06.003. Epub 2015 Jul 16. Cancer Cell. 2015. PMID: 26190263 Free PMC article.

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