Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation.
Snaebjornsson MT, Poeller P, Komkova D, Röhrig F, Schlicker L, Winkelkotte AM, Chaves-Filho AB, Al-Shami KM, Caballero CD, Koltsaki I, Vogel FCE, Frias-Soler RC, Rudalska R, Schwarz JD, Wolf E, Dauch D, Steuer R, Schulze A.
Snaebjornsson MT, et al. Among authors: wolf e.
Nat Metab. 2025 Jan 20. doi: 10.1038/s42255-024-01201-w. Online ahead of print.
Nat Metab. 2025.
PMID: 39833612