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Hypericin affects cancer side populations via competitive inhibition of BCRP.
Vargová J, Mikeš J, Jendželovský R, Mikešová L, Kuchárová B, Čulka Ľ, Fedr R, Remšík J, Souček K, Kozubík A, Fedoročko P. Vargová J, et al. Among authors: jendzelovsky r. Biomed Pharmacother. 2018 Mar;99:511-522. doi: 10.1016/j.biopha.2018.01.074. Epub 2018 Feb 20. Biomed Pharmacother. 2018. PMID: 29665654
Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin.
Mikeš J, Hýžďalová M, Kočí L, Jendželovský R, Kovaľ J, Vaculová A, Hofmanová J, Kozubík A, Fedoročko P. Mikeš J, et al. Among authors: jendzelovsky r. Photochem Photobiol Sci. 2011 Apr;10(4):626-32. doi: 10.1039/c0pp00359j. Epub 2011 Feb 4. Photochem Photobiol Sci. 2011. PMID: 21298151
3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents.
Plsikova J, Janovec L, Koval J, Ungvarsky J, Mikes J, Jendzelovsky R, Fedorocko P, Imrich J, Kristian P, Kasparkova J, Brabec V, Kozurkova M. Plsikova J, et al. Among authors: jendzelovsky r. Eur J Med Chem. 2012 Nov;57:283-95. doi: 10.1016/j.ejmech.2012.09.020. Epub 2012 Sep 23. Eur J Med Chem. 2012. PMID: 23072739
46 results