Chua NK - Search Results

1

Cholesterol, cancer, and rebooting a treatment for athlete's foot.

Chua NK, Coates HW, Brown AJ. Chua NK, et al. Sci Transl Med. 2018 Apr 18;10(437):eaat3741. doi: 10.1126/scitranslmed.aat3741. Sci Transl Med. 2018. PMID: 29669852 Review.

2

Squalene monooxygenase: a journey to the heart of cholesterol synthesis.

Chua NK, Coates HW, Brown AJ. Chua NK, et al. Prog Lipid Res. 2020 Jul;79:101033. doi: 10.1016/j.plipres.2020.101033. Epub 2020 Apr 28. Prog Lipid Res. 2020. PMID: 32360125 Review.

3

The Regulatory Domain of Squalene Monooxygenase Contains a Re-entrant Loop and Senses Cholesterol via a Conformational Change.

Howe V, Chua NK, Stevenson J, Brown AJ. Howe V, et al. Among authors: chua nk. J Biol Chem. 2015 Nov 13;290(46):27533-44. doi: 10.1074/jbc.M115.675181. Epub 2015 Oct 3. J Biol Chem. 2015. PMID: 26434806 Free PMC article.

4

Cholesterol homeostasis: How do cells sense sterol excess?

Howe V, Sharpe LJ, Alexopoulos SJ, Kunze SV, Chua NK, Li D, Brown AJ. Howe V, et al. Among authors: chua nk. Chem Phys Lipids. 2016 Sep;199:170-178. doi: 10.1016/j.chemphyslip.2016.02.011. Epub 2016 Mar 15. Chem Phys Lipids. 2016. PMID: 26993747 Review.

5

A conserved degron containing an amphipathic helix regulates the cholesterol-mediated turnover of human squalene monooxygenase, a rate-limiting enzyme in cholesterol synthesis.

Chua NK, Howe V, Jatana N, Thukral L, Brown AJ. Chua NK, et al. J Biol Chem. 2017 Dec 8;292(49):19959-19973. doi: 10.1074/jbc.M117.794230. Epub 2017 Sep 27. J Biol Chem. 2017. PMID: 28972164 Free PMC article.

6

Lipid sensing tips the balance for a key cholesterol synthesis enzyme.

Chua NK, Brown AJ. Chua NK, et al. J Lipid Res. 2020 Nov;61(11):1363. doi: 10.1194/jlr.ILR120000801. Epub 2020 May 5. J Lipid Res. 2020. PMID: 32371565 Free PMC article. No abstract available.

7

Mallostery: Filling a niche between quality and metabolic control.

Chua NK, Brown AJ. Chua NK, et al. J Biol Chem. 2018 Sep 21;293(38):14951-14952. doi: 10.1074/jbc.H118.005031. J Biol Chem. 2018. PMID: 30242042 Free PMC article.

8

The shape of human squalene epoxidase expands the arsenal against cancer.

Brown AJ, Chua NK, Yan N. Brown AJ, et al. Among authors: chua nk. Nat Commun. 2019 Feb 21;10(1):888. doi: 10.1038/s41467-019-08866-y. Nat Commun. 2019. PMID: 30792392 Free PMC article. Review.

9

Non-canonical ubiquitination of the cholesterol-regulated degron of squalene monooxygenase.

Chua NK, Hart-Smith G, Brown AJ. Chua NK, et al. J Biol Chem. 2019 May 17;294(20):8134-8147. doi: 10.1074/jbc.RA119.007798. Epub 2019 Apr 2. J Biol Chem. 2019. PMID: 30940729 Free PMC article.

10

Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene.

Coates HW, Chua NK, Brown AJ. Coates HW, et al. Among authors: chua nk. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Nov;1864(11):1656-1668. doi: 10.1016/j.bbalip.2019.08.006. Epub 2019 Aug 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31422115

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

20 results

Search Page

Filters