Chen ZZ - Search Results

1

Functionalized Spiroindolines with Anticancer Activity through a Metal-Free Post-Ugi Diastereoselective One-Pot Cascade Reaction.

Xu ZG, Li SQ, Meng JP, Tang DY, He LJ, Lei J, Lin HK, Li HY, Chen ZZ. Xu ZG, et al. Among authors: chen zz. Chemistry. 2018 May 7;24(26):6732-6736. doi: 10.1002/chem.201801081. Epub 2018 Apr 20. Chemistry. 2018. PMID: 29676029 Free PMC article.

2

Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology.

Frett B, Carlomagno F, Moccia ML, Brescia A, Federico G, De Falco V, Admire B, Chen Z, Qi W, Santoro M, Li HY. Frett B, et al. Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8717-21. doi: 10.1002/anie.201501104. Epub 2015 Jun 30. Angew Chem Int Ed Engl. 2015. PMID: 26126987 Free PMC article.

3

Facile microwave-assisted synthesis of benzimidazole scaffolds via Ugi-type three-component condensation (3CC) reactions.

Song GT, Xu ZG, Tang DY, Li SQ, Xie ZG, Zhong HL, Yang ZW, Zhu J, Zhang J, Chen ZZ. Song GT, et al. Among authors: chen zz. Mol Divers. 2016 May;20(2):575-80. doi: 10.1007/s11030-015-9646-7. Epub 2015 Nov 18. Mol Divers. 2016. PMID: 26577113

4

An Efficient and Facile Method for the Synthesis of Benzimidazoisoquinoline Derivatives via a Multicomponent Reaction.

Liao WL, Li SQ, Wang J, Zhang ZY, Yang ZW, Xu D, Xu C, Lan HT, Chen ZZ, Xu ZG. Liao WL, et al. Among authors: chen zz. ACS Comb Sci. 2016 Jan 11;18(1):65-9. doi: 10.1021/acscombsci.5b00145. Epub 2015 Dec 18. ACS Comb Sci. 2016. PMID: 26634875

5

Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation.

Lei J, Xu ZG, Li SQ, Xu J, Zhu J, Chen ZZ. Lei J, et al. Among authors: chen zz. Mol Divers. 2016 Nov;20(4):859-865. doi: 10.1007/s11030-016-9679-6. Epub 2016 Jun 7. Mol Divers. 2016. PMID: 27272954

6

Efficient Synthesis of Fused Oxazepino-isoquinoline Scaffolds via an Ugi, Followed by an Intramolecular Cyclization.

Li Y, Meng JP, Lei J, Chen ZZ, Tang DY, Zhu J, Zhang J, Xu ZG. Li Y, et al. Among authors: chen zz. ACS Comb Sci. 2017 May 8;19(5):324-330. doi: 10.1021/acscombsci.7b00002. Epub 2017 Mar 16. ACS Comb Sci. 2017. PMID: 28271876

7

Recent advances in the development of polycyclic skeletons via Ugi reaction cascades.

Lei J, Meng JP, Tang DY, Frett B, Chen ZZ, Xu ZG. Lei J, et al. Among authors: chen zz. Mol Divers. 2018 May;22(2):503-516. doi: 10.1007/s11030-017-9811-2. Epub 2018 Jan 16. Mol Divers. 2018. PMID: 29340996 Review.

8

Acid-Promoted One-Pot Synthesis of Substituted Furan and 6-Methylpyrazin-2(1 H)-one Derivatives via Allene Intermediate Formed in Situ.

Lei J, Xu ZG, Tang DY, Li Y, Xu J, Li HY, Zhu J, Chen ZZ. Lei J, et al. Among authors: chen zz. ACS Comb Sci. 2018 May 14;20(5):292-297. doi: 10.1021/acscombsci.8b00005. Epub 2018 Apr 11. ACS Comb Sci. 2018. PMID: 29620860

9

Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.

He LJ, Yang DL, Li SQ, Zhang YJ, Tang Y, Lei J, Frett B, Lin HK, Li HY, Chen ZZ, Xu ZG. He LJ, et al. Among authors: chen zz. Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908. doi: 10.1016/j.bmc.2018.06.010. Epub 2018 Jun 12. Bioorg Med Chem. 2018. PMID: 29921474 Free PMC article.

10

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways.

Zhang YJ, Xu ZG, Li SQ, He LJ, Tang Y, Chen ZZ, Yang DL. Zhang YJ, et al. Among authors: chen zz. Cancer Cell Int. 2018 Jun 28;18:90. doi: 10.1186/s12935-018-0588-x. eCollection 2018. Cancer Cell Int. 2018. PMID: 29988358 Free PMC article.

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