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Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Mertens J, et al. Among authors: toda t. Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8. Cell Stem Cell. 2015. PMID: 26456686 Free PMC article.
Adult Hippocampal Neurogenesis: A Coming-of-Age Story.
Kuhn HG, Toda T, Gage FH. Kuhn HG, et al. Among authors: toda t. J Neurosci. 2018 Dec 5;38(49):10401-10410. doi: 10.1523/JNEUROSCI.2144-18.2018. Epub 2018 Oct 31. J Neurosci. 2018. PMID: 30381404 Free PMC article. Review.
Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis.
Bedrosian TA, Houtman J, Eguiguren JS, Ghassemzadeh S, Rund N, Novaresi NM, Hu L, Parylak SL, Denli AM, Randolph-Moore L, Namba T, Gage FH, Toda T. Bedrosian TA, et al. Among authors: toda t. EMBO J. 2021 Feb 1;40(3):e105819. doi: 10.15252/embj.2020105819. Epub 2020 Dec 10. EMBO J. 2021. PMID: 33300615 Free PMC article.
Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation.
Toda T, Bedrosian TA, Schafer ST, Cuoco MS, Linker SB, Ghassemzadeh S, Mitchell L, Whiteley JT, Novaresi N, McDonald AH, Gallina IS, Yoon H, Hester ME, Pena M, Lim C, Suljic E, AlFatah Mansour A, Boulard M, Parylak SL, Gage FH. Toda T, et al. Cell Rep. 2024 Feb 27;43(2):113774. doi: 10.1016/j.celrep.2024.113774. Epub 2024 Feb 13. Cell Rep. 2024. PMID: 38349791 Free PMC article.
Lifelong persistence of nuclear RNAs in the mouse brain.
Zocher S, McCloskey A, Karasinsky A, Schulte R, Friedrich U, Lesche M, Rund N, Gage FH, Hetzer MW, Toda T. Zocher S, et al. Among authors: toda t. Science. 2024 Apr 5;384(6691):53-59. doi: 10.1126/science.adf3481. Epub 2024 Apr 4. Science. 2024. PMID: 38574132 Free PMC article.
1,387 results