Liu Y - Search Results

1

Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4.

Li C, Deng X, Zhang W, Xie X, Conrad M, Liu Y, Angeli JPF, Lai L. Li C, et al. Among authors: liu y. J Med Chem. 2019 Jan 10;62(1):266-275. doi: 10.1021/acs.jmedchem.8b00315. Epub 2018 May 2. J Med Chem. 2019. PMID: 29688708

2

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy.

Li C, Deng X, Xie X, Liu Y, Friedmann Angeli JP, Lai L. Li C, et al. Among authors: liu y. Front Pharmacol. 2018 Oct 3;9:1120. doi: 10.3389/fphar.2018.01120. eCollection 2018. Front Pharmacol. 2018. PMID: 30337875 Free PMC article.

3

Molecular mechanism of 15-lipoxygenase allosteric activation and inhibition.

Meng H , Dai Z , Zhang W , Liu Y , Lai L . Meng H , et al. Among authors: liu y. Phys Chem Chem Phys. 2018 May 30;20(21):14785-14795. doi: 10.1039/c7cp08586a. Phys Chem Chem Phys. 2018. PMID: 29780994

4

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds.

Liu P, Liu H, Sun Q, Liang H, Li C, Deng X, Liu Y, Lai L. Liu P, et al. Among authors: liu y, liu h. Eur J Med Chem. 2020 Nov 15;206:112702. doi: 10.1016/j.ejmech.2020.112702. Epub 2020 Aug 1. Eur J Med Chem. 2020. PMID: 32798789 Free PMC article.

5

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors.

Deng X, Zhang X, Tang B, Liu H, Shen Q, Liu Y, Lai L. Deng X, et al. Among authors: liu y, liu h. Front Chem. 2018 Apr 4;6:98. doi: 10.3389/fchem.2018.00098. eCollection 2018. Front Chem. 2018. PMID: 29670876 Free PMC article.

6

Targeting intrinsically disordered proteins at the edge of chaos.

Ruan H, Sun Q, Zhang W, Liu Y, Lai L. Ruan H, et al. Among authors: liu y. Drug Discov Today. 2019 Jan;24(1):217-227. doi: 10.1016/j.drudis.2018.09.017. Epub 2018 Sep 29. Drug Discov Today. 2019. PMID: 30278223 Review.

7

Discovery of Small Molecule Inhibitors Targeting the Sonic Hedgehog.

Yun T, Wang J, Yang J, Huang W, Lai L, Tan W, Liu Y. Yun T, et al. Among authors: liu y. Front Chem. 2020 Jun 16;8:498. doi: 10.3389/fchem.2020.00498. eCollection 2020. Front Chem. 2020. PMID: 32612978 Free PMC article.

8

Computational strategy for intrinsically disordered protein ligand design leads to the discovery of p53 transactivation domain I binding compounds that activate the p53 pathway.

Ruan H, Yu C, Niu X, Zhang W, Liu H, Chen L, Xiong R, Sun Q, Jin C, Liu Y, Lai L. Ruan H, et al. Among authors: liu y, liu h. Chem Sci. 2020 Dec 28;12(8):3004-3016. doi: 10.1039/d0sc04670a. Chem Sci. 2020. PMID: 34164069 Free PMC article.

9

Integrative structural modeling of a multidomain polo-like kinase.

Ruan H , Kiselar J , Zhang W , Li S , Xiong R , Liu Y , Yang S , Lai L . Ruan H , et al. Among authors: liu y. Phys Chem Chem Phys. 2020 Dec 16;22(47):27581-27589. doi: 10.1039/d0cp05030j. Phys Chem Chem Phys. 2020. PMID: 33236741

10

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism.

Reid MA, Allen AE, Liu S, Liberti MV, Liu P, Liu X, Dai Z, Gao X, Wang Q, Liu Y, Lai L, Locasale JW. Reid MA, et al. Among authors: liu y, liu x, liu s, liu p. Nat Commun. 2018 Dec 21;9(1):5442. doi: 10.1038/s41467-018-07868-6. Nat Commun. 2018. PMID: 30575741 Free PMC article.

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