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Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.
Forbes TA, Howden SE, Lawlor K, Phipson B, Maksimovic J, Hale L, Wilson S, Quinlan C, Ho G, Holman K, Bennetts B, Crawford J, Trnka P, Oshlack A, Patel C, Mallett A, Simons C, Little MH. Forbes TA, et al. Among authors: howden se. Am J Hum Genet. 2018 May 3;102(5):816-831. doi: 10.1016/j.ajhg.2018.03.014. Epub 2018 Apr 26. Am J Hum Genet. 2018. PMID: 29706353 Free PMC article.
Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo.
van den Berg CW, Ritsma L, Avramut MC, Wiersma LE, van den Berg BM, Leuning DG, Lievers E, Koning M, Vanslambrouck JM, Koster AJ, Howden SE, Takasato M, Little MH, Rabelink TJ. van den Berg CW, et al. Among authors: howden se. Stem Cell Reports. 2018 Mar 13;10(3):751-765. doi: 10.1016/j.stemcr.2018.01.041. Epub 2018 Mar 1. Stem Cell Reports. 2018. PMID: 29503086 Free PMC article.
Evaluation of variability in human kidney organoids.
Phipson B, Er PX, Combes AN, Forbes TA, Howden SE, Zappia L, Yen HJ, Lawlor KT, Hale LJ, Sun J, Wolvetang E, Takasato M, Oshlack A, Little MH. Phipson B, et al. Among authors: howden se. Nat Methods. 2019 Jan;16(1):79-87. doi: 10.1038/s41592-018-0253-2. Epub 2018 Dec 20. Nat Methods. 2019. PMID: 30573816 Free PMC article.
Generating Kidney from Stem Cells.
Little MH, Hale LJ, Howden SE, Kumar SV. Little MH, et al. Among authors: howden se. Annu Rev Physiol. 2019 Feb 10;81:335-357. doi: 10.1146/annurev-physiol-020518-114331. Annu Rev Physiol. 2019. PMID: 30742789 Review.
Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1.
Vanslambrouck JM, Woodard LE, Suhaimi N, Williams FM, Howden SE, Wilson SB, Lonsdale A, Er PX, Li J, Maksimovic J, Oshlack A, Wilson MH, Little MH. Vanslambrouck JM, et al. Among authors: howden se. Kidney Int. 2019 May;95(5):1153-1166. doi: 10.1016/j.kint.2018.11.041. Epub 2019 Feb 28. Kidney Int. 2019. PMID: 30827514 Free PMC article.
51 results