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A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells.
Fang F, Angulo B, Xia N, Sukhwani M, Wang Z, Carey CC, Mazurie A, Cui J, Wilkinson R, Wiedenheft B, Irie N, Surani MA, Orwig KE, Reijo Pera RA. Fang F, et al. Among authors: irie n. Nat Cell Biol. 2018 Jun;20(6):655-665. doi: 10.1038/s41556-018-0094-3. Epub 2018 Apr 30. Nat Cell Biol. 2018. PMID: 29713018 Free PMC article.
SOX17 is a critical specifier of human primordial germ cell fate.
Irie N, Weinberger L, Tang WW, Kobayashi T, Viukov S, Manor YS, Dietmann S, Hanna JH, Surani MA. Irie N, et al. Cell. 2015 Jan 15;160(1-2):253-68. doi: 10.1016/j.cell.2014.12.013. Epub 2014 Dec 24. Cell. 2015. PMID: 25543152 Free PMC article.
Germline competency of human embryonic stem cells depends on eomesodermin.
Chen D, Liu W, Lukianchikov A, Hancock GV, Zimmerman J, Lowe MG, Kim R, Galic Z, Irie N, Surani MA, Jacobsen SE, Clark AT. Chen D, et al. Among authors: irie n. Biol Reprod. 2017 Jan 1;97(6):850-861. doi: 10.1093/biolre/iox138. Biol Reprod. 2017. PMID: 29091993 Free PMC article.
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.
Floros VI, Pyle A, Dietmann S, Wei W, Tang WCW, Irie N, Payne B, Capalbo A, Noli L, Coxhead J, Hudson G, Crosier M, Strahl H, Khalaf Y, Saitou M, Ilic D, Surani MA, Chinnery PF. Floros VI, et al. Among authors: irie n. Nat Cell Biol. 2018 Feb;20(2):144-151. doi: 10.1038/s41556-017-0017-8. Epub 2018 Jan 15. Nat Cell Biol. 2018. PMID: 29335530 Free PMC article.
118 results