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Page 1
A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells.
Fang F, Angulo B, Xia N, Sukhwani M, Wang Z, Carey CC, Mazurie A, Cui J, Wilkinson R, Wiedenheft B, Irie N, Surani MA, Orwig KE, Reijo Pera RA. Fang F, et al. Among authors: wiedenheft b. Nat Cell Biol. 2018 Jun;20(6):655-665. doi: 10.1038/s41556-018-0094-3. Epub 2018 Apr 30. Nat Cell Biol. 2018. PMID: 29713018 Free PMC article.
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA. Adler BA, et al. Among authors: wiedenheft b. Nucleic Acids Res. 2024 Jan 5;52(D1):D590-D596. doi: 10.1093/nar/gkad890. Nucleic Acids Res. 2024. PMID: 37889041 Free PMC article.
The retrotransposon - derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity.
Wood TWP, Henriques WS, Cullen HB, Romero M, Blengini CS, Sarathy S, Sorkin J, Bekele H, Jin C, Kim S, Chemiakine A, Khondker RC, Isola JVV, Stout MB, Gennarino VA, Mogessie B, Jain D, Schindler K, Suh Y, Wiedenheft B, Berchowitz LE. Wood TWP, et al. Among authors: wiedenheft b. bioRxiv [Preprint]. 2024 May 14:2024.05.11.592987. doi: 10.1101/2024.05.11.592987. bioRxiv. 2024. PMID: 38798495 Free PMC article. Preprint.
A CRISPR method for genome engineering.
Wilkinson R, Wiedenheft B. Wilkinson R, et al. Among authors: wiedenheft b. F1000Prime Rep. 2014 Jan 2;6:3. doi: 10.12703/P6-3. eCollection 2014. F1000Prime Rep. 2014. PMID: 24592315 Free PMC article. Review.
The history and market impact of CRISPR RNA-guided nucleases.
van Erp PB, Bloomer G, Wilkinson R, Wiedenheft B. van Erp PB, et al. Among authors: wiedenheft b. Curr Opin Virol. 2015 Jun;12:85-90. doi: 10.1016/j.coviro.2015.03.011. Epub 2015 Apr 26. Curr Opin Virol. 2015. PMID: 25914022 Free PMC article.
Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System.
Qazi S, Miettinen HM, Wilkinson RA, McCoy K, Douglas T, Wiedenheft B. Qazi S, et al. Among authors: wiedenheft b. Mol Pharm. 2016 Mar 7;13(3):1191-6. doi: 10.1021/acs.molpharmaceut.5b00822. Epub 2016 Feb 22. Mol Pharm. 2016. PMID: 26894836 Free PMC article.
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.
Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Rollins MF, et al. Among authors: wiedenheft b. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5113-E5121. doi: 10.1073/pnas.1616395114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28438998 Free PMC article.
CRISPR RNA-guided autonomous delivery of Cas9.
Wilkinson RA, Martin C, Nemudryi AA, Wiedenheft B. Wilkinson RA, et al. Among authors: wiedenheft b. Nat Struct Mol Biol. 2019 Jan;26(1):14-24. doi: 10.1038/s41594-018-0173-y. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598555 Free PMC article. Review.
89 results