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Divergent effects of strontium and calcium-sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity.
Diepenhorst NA, Leach K, Keller AN, Rueda P, Cook AE, Pierce TL, Nowell C, Pastoureau P, Sabatini M, Summers RJ, Charman WN, Sexton PM, Christopoulos A, Langmead CJ. Diepenhorst NA, et al. Among authors: summers rj. Br J Pharmacol. 2018 Nov;175(21):4095-4108. doi: 10.1111/bph.14344. Epub 2018 Jun 3. Br J Pharmacol. 2018. PMID: 29714810 Free PMC article.
Relaxin receptors--new drug targets for multiple disease states.
Van Der Westhuizen ET, Summers RJ, Halls ML, Bathgate RA, Sexton PM. Van Der Westhuizen ET, et al. Among authors: summers rj. Curr Drug Targets. 2007 Jan;8(1):91-104. doi: 10.2174/138945007779315650. Curr Drug Targets. 2007. PMID: 17266534 Review.
Atypical pharmacologies at beta-adrenoceptors.
Summers RJ. Summers RJ. Br J Pharmacol. 2008 Oct;155(3):285-7. doi: 10.1038/bjp.2008.293. Epub 2008 Jul 21. Br J Pharmacol. 2008. PMID: 18641673 Free PMC article.
Ligand-directed signalling at beta-adrenoceptors.
Evans BA, Sato M, Sarwar M, Hutchinson DS, Summers RJ. Evans BA, et al. Among authors: summers rj. Br J Pharmacol. 2010 Mar;159(5):1022-38. doi: 10.1111/j.1476-5381.2009.00602.x. Epub 2010 Feb 2. Br J Pharmacol. 2010. PMID: 20132209 Free PMC article. Review.
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.
Koole C, Wootten D, Simms J, Valant C, Sridhar R, Woodman OL, Miller LJ, Summers RJ, Christopoulos A, Sexton PM. Koole C, et al. Among authors: summers rj. Mol Pharmacol. 2010 Sep;78(3):456-65. doi: 10.1124/mol.110.065664. Epub 2010 Jun 14. Mol Pharmacol. 2010. PMID: 20547734 Free PMC article.
352 results