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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.
Tarragó MG, Chini CCS, Kanamori KS, Warner GM, Caride A, de Oliveira GC, Rud M, Samani A, Hein KZ, Huang R, Jurk D, Cho DS, Boslett JJ, Miller JD, Zweier JL, Passos JF, Doles JD, Becherer DJ, Chini EN. Tarragó MG, et al. Among authors: caride a. Cell Metab. 2018 May 1;27(5):1081-1095.e10. doi: 10.1016/j.cmet.2018.03.016. Cell Metab. 2018. PMID: 29719225 Free PMC article.
The plasma membrane Ca2+ pump isoform 4a differs from isoform 4b in the mechanism of calmodulin binding and activation kinetics: implications for Ca2+ signaling.
Caride AJ, Filoteo AG, Penniston JT, Strehler EE. Caride AJ, et al. J Biol Chem. 2007 Aug 31;282(35):25640-8. doi: 10.1074/jbc.M701129200. Epub 2007 Jun 26. J Biol Chem. 2007. PMID: 17595168 Free PMC article.
TA-CaM binds to two conformations of PMCA4a, an "open" conformation with high activity, and a "closed" one with lower activity. Compared with PMCA4b (Penheiter, A. R., Bajzer, Z., Filoteo, A. G., Thorogate, R., Torok, K., and Caride, A. J. (2003 …
TA-CaM binds to two conformations of PMCA4a, an "open" conformation with high activity, and a "closed" one with lower activity. Compa …
116 results