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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.
Tarragó MG, Chini CCS, Kanamori KS, Warner GM, Caride A, de Oliveira GC, Rud M, Samani A, Hein KZ, Huang R, Jurk D, Cho DS, Boslett JJ, Miller JD, Zweier JL, Passos JF, Doles JD, Becherer DJ, Chini EN. Tarragó MG, et al. Among authors: de oliveira gc. Cell Metab. 2018 May 1;27(5):1081-1095.e10. doi: 10.1016/j.cmet.2018.03.016. Cell Metab. 2018. PMID: 29719225 Free PMC article.
Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) Intracellular Levels: Enzymatic Coupled Cycling Assay and Ultra-performance Liquid Chromatography (UPLC)-Mass Spectrometry.
Kanamori KS, de Oliveira GC, Auxiliadora-Martins M, Schoon RA, Reid JM, Chini EN. Kanamori KS, et al. Among authors: de oliveira gc. Bio Protoc. 2018 Jul 20;8(14):e2937. doi: 10.21769/BioProtoc.2937. Bio Protoc. 2018. PMID: 30101155 Free PMC article.
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, Kanamori KS, Witte MA, Vidal P, Kirkland AL, De Cecco M, Chellappa K, McReynolds MR, Jankowski C, Tchkonia T, Kirkland JL, Sedivy JM, van Deursen JM, Baker DJ, van Schooten W, Rabinowitz JD, Baur JA, Chini EN. Chini CCS, et al. Among authors: de cecco m, de oliveira gc. Nat Metab. 2020 Nov;2(11):1284-1304. doi: 10.1038/s42255-020-00298-z. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199925 Free PMC article.
Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis.
Shi B, Wang W, Korman B, Kai L, Wang Q, Wei J, Bale S, Marangoni RG, Bhattacharyya S, Miller S, Xu D, Akbarpour M, Cheresh P, Proccissi D, Gursel D, Espindola-Netto JM, Chini CCS, de Oliveira GC, Gudjonsson JE, Chini EN, Varga J. Shi B, et al. Among authors: de oliveira gc. iScience. 2020 Dec 7;24(1):101902. doi: 10.1016/j.isci.2020.101902. eCollection 2021 Jan 22. iScience. 2020. PMID: 33385109 Free PMC article.
Erratum: Correction Notice: Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) Intracellular Levels: Enzymatic Coupled Cycling Assay and Ultra-performance Liquid Chromatography (UPLC)-Mass Spectrometry.
Kanamori KS, de Oliveira GC, Auxiliadora-Martins M, Schoon RA, Reid JM, Chini EN. Kanamori KS, et al. Among authors: de oliveira gc. Bio Protoc. 2019 Jun 5;9(11):e3272. doi: 10.21769/BioProtoc.3272. eCollection 2019 Jun 5. Bio Protoc. 2019. PMID: 38155818 Free PMC article.
Angiotensin-(1-7) infusion in COVID-19 patients admitted to the ICU: a seamless phase 1-2 randomized clinical trial.
Martins ALV, Annoni F, da Silva FA, Bolais-Ramos L, de Oliveira GC, Ribeiro RC, Diniz MML, Silva TGF, Pinheiro BD, Rodrigues NA, Dos Santos Matos AH, Motta-Santos D, Campagnole-Santos MJ, Verano-Braga T, Taccone FS, Santos RAS. Martins ALV, et al. Among authors: de oliveira gc. Ann Intensive Care. 2024 Sep 4;14(1):139. doi: 10.1186/s13613-024-01369-0. Ann Intensive Care. 2024. PMID: 39231898 Free PMC article.
78 results