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252 results

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Page 1
Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.
Funck-Brentano T, Nilsson KH, Brommage R, Henning P, Lerner UH, Koskela A, Tuukkanen J, Cohen-Solal M, Movérare-Skrtic S, Ohlsson C. Funck-Brentano T, et al. Among authors: lerner uh. J Endocrinol. 2018 Jul;238(1):13-23. doi: 10.1530/JOE-18-0153. Epub 2018 May 2. J Endocrinol. 2018. PMID: 29720540 Free PMC article.
WNT16 overexpression partly protects against glucocorticoid-induced bone loss.
Ohlsson C, Nilsson KH, Henning P, Wu J, Gustafsson KL, Poutanen M, Lerner UH, Movérare-Skrtic S. Ohlsson C, et al. Among authors: lerner uh. Am J Physiol Endocrinol Metab. 2018 Jun 1;314(6):E597-E604. doi: 10.1152/ajpendo.00292.2017. Epub 2018 Feb 6. Am J Physiol Endocrinol Metab. 2018. PMID: 29406783 Free article.
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice.
Ohlsson C, Henning P, Nilsson KH, Wu J, Gustafsson KL, Sjögren K, Törnqvist A, Koskela A, Zhang FP, Lagerquist MK, Poutanen M, Tuukkanen J, Lerner UH, Movérare-Skrtic S. Ohlsson C, et al. Among authors: lerner uh. J Endocrinol. 2018 May;237(2):113-122. doi: 10.1530/JOE-18-0020. Epub 2018 Mar 12. J Endocrinol. 2018. PMID: 29530924 Free PMC article.
Clinically relevant doses of vitamin A decrease cortical bone mass in mice.
Lionikaite V, Gustafsson KL, Westerlund A, Windahl SH, Koskela A, Tuukkanen J, Johansson H, Ohlsson C, Conaway HH, Henning P, Lerner UH. Lionikaite V, et al. Among authors: lerner uh. J Endocrinol. 2018 Oct 31;239(3):389-402. doi: 10.1530/JOE-18-0316. J Endocrinol. 2018. PMID: 30388359 Free PMC article.
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans.
Movérare-Skrtic S, Nilsson KH, Henning P, Funck-Brentano T, Nethander M, Rivadeneira F, Coletto Nunes G, Koskela A, Tuukkanen J, Tuckermann J, Perret C, Souza PPC, Lerner UH, Ohlsson C. Movérare-Skrtic S, et al. Among authors: lerner uh. FASEB J. 2019 Oct;33(10):11163-11179. doi: 10.1096/fj.201900707R. Epub 2019 Jul 15. FASEB J. 2019. PMID: 31307226 Free PMC article.
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in mice.
Nilsson KH, Henning P, El Shahawy M, Wu J, Koskela A, Tuukkanen J, Perret C, Lerner UH, Ohlsson C, Movérare-Skrtic S. Nilsson KH, et al. Among authors: lerner uh. Am J Physiol Endocrinol Metab. 2021 May 1;320(5):E967-E975. doi: 10.1152/ajpendo.00565.2020. Epub 2021 Mar 22. Am J Physiol Endocrinol Metab. 2021. PMID: 33749332 Free article.
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other.
Nilsson KH, Wu J, Gustafsson KL, El Shahawy M, Koskela A, Tuukkanen J, Tuckermann J, Henning P, Lerner UH, Ohlsson C, Movérare-Skrtic S. Nilsson KH, et al. Among authors: lerner uh. Am J Physiol Endocrinol Metab. 2022 Mar 1;322(3):E211-E218. doi: 10.1152/ajpendo.00383.2021. Epub 2022 Jan 24. Am J Physiol Endocrinol Metab. 2022. PMID: 35068191 Free PMC article.
RSPO3 is important for trabecular bone and fracture risk in mice and humans.
Nilsson KH, Henning P, El Shahawy M, Nethander M, Andersen TL, Ejersted C, Wu J, Gustafsson KL, Koskela A, Tuukkanen J, Souza PPC, Tuckermann J, Lorentzon M, Ruud LE, Lehtimäki T, Tobias JH, Zhou S, Lerner UH, Richards JB, Movérare-Skrtic S, Ohlsson C. Nilsson KH, et al. Among authors: lerner uh. Nat Commun. 2021 Aug 13;12(1):4923. doi: 10.1038/s41467-021-25124-2. Nat Commun. 2021. PMID: 34389713 Free PMC article.
The gut microbiota regulates bone mass in mice.
Sjögren K, Engdahl C, Henning P, Lerner UH, Tremaroli V, Lagerquist MK, Bäckhed F, Ohlsson C. Sjögren K, et al. Among authors: lerner uh. J Bone Miner Res. 2012 Jun;27(6):1357-67. doi: 10.1002/jbmr.1588. J Bone Miner Res. 2012. PMID: 22407806 Free PMC article.
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures.
Movérare-Skrtic S, Henning P, Liu X, Nagano K, Saito H, Börjesson AE, Sjögren K, Windahl SH, Farman H, Kindlund B, Engdahl C, Koskela A, Zhang FP, Eriksson EE, Zaman F, Hammarstedt A, Isaksson H, Bally M, Kassem A, Lindholm C, Sandberg O, Aspenberg P, Sävendahl L, Feng JQ, Tuckermann J, Tuukkanen J, Poutanen M, Baron R, Lerner UH, Gori F, Ohlsson C. Movérare-Skrtic S, et al. Among authors: lerner uh. Nat Med. 2014 Nov;20(11):1279-88. doi: 10.1038/nm.3654. Epub 2014 Oct 12. Nat Med. 2014. PMID: 25306233 Free PMC article.
252 results