Hansen S - Search Results

1

Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.

Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, Wang W, de Sauvage FJ, Hannoush RN. Nile AH, et al. Among authors: hansen s. Nat Chem Biol. 2018 Sep;14(9):902. doi: 10.1038/s41589-018-0069-5. Nat Chem Biol. 2018. PMID: 29728602

2

A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.

Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, Wang W, de Sauvage FJ, Hannoush RN. Nile AH, et al. Among authors: hansen s. Nat Chem Biol. 2018 Jun;14(6):582-590. doi: 10.1038/s41589-018-0035-2. Epub 2018 Apr 9. Nat Chem Biol. 2018. PMID: 29632413

3

Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate Clostridium difficile Toxin B Pathogenicity in Epithelial Cells.

Hansen S, Nile AH, Mehta SC, Fuhrmann J, Hannoush RN. Hansen S, et al. J Med Chem. 2019 Sep 12;62(17):7739-7750. doi: 10.1021/acs.jmedchem.9b00500. Epub 2019 Sep 3. J Med Chem. 2019. PMID: 31429553

4

It Takes Two to Regenerate: Optimizing Custom Wnt Surrogates.

Hansen S, Hannoush RN. Hansen S, et al. Cell Chem Biol. 2020 May 21;27(5):473-475. doi: 10.1016/j.chembiol.2020.05.004. Cell Chem Biol. 2020. PMID: 32442412 Free article.

5

Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signaling.

Hansen S, Zhang Y, Hwang S, Nabhan A, Li W, Fuhrmann J, Kschonsak Y, Zhou L, Nile AH, Gao X, Piskol R, de Sousa E Melo F, de Sauvage FJ, Hannoush RN. Hansen S, et al. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2207327119. doi: 10.1073/pnas.2207327119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343233 Free PMC article.

6

Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.

Yun J, Hansen S, Morris O, Madden DT, Libeu CP, Kumar AJ, Wehrfritz C, Nile AH, Zhang Y, Zhou L, Liang Y, Modrusan Z, Chen MB, Overall CC, Garfield D, Campisi J, Schilling B, Hannoush RN, Jasper H. Yun J, et al. Among authors: hansen s. Nat Commun. 2023 Jan 11;14(1):156. doi: 10.1038/s41467-022-35487-9. Nat Commun. 2023. PMID: 36631445 Free PMC article.

7

Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering.

Thakur AK, Miller SE, Liau NPD, Hwang S, Hansen S, de Sousa E Melo F, Sudhamsu J, Hannoush RN. Thakur AK, et al. Among authors: hansen s. ACS Chem Biol. 2023 Apr 21;18(4):772-784. doi: 10.1021/acschembio.2c00753. Epub 2023 Mar 9. ACS Chem Biol. 2023. PMID: 36893429

8

Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.

Tsutsumi N, Hwang S, Waghray D, Hansen S, Jude KM, Wang N, Miao Y, Glassman CR, Caveney NA, Janda CY, Hannoush RN, Garcia KC. Tsutsumi N, et al. Among authors: hansen s. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2218238120. doi: 10.1073/pnas.2218238120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893265 Free PMC article.

9

Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly.

O'Brien LE, Jou TS, Pollack AL, Zhang Q, Hansen SH, Yurchenco P, Mostov KE. O'Brien LE, et al. Among authors: hansen sh. Nat Cell Biol. 2001 Sep;3(9):831-8. doi: 10.1038/ncb0901-831. Nat Cell Biol. 2001. PMID: 11533663

10

Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.

Hansen SH, Zegers MM, Woodrow M, Rodriguez-Viciana P, Chardin P, Mostov KE, McMahon M. Hansen SH, et al. Mol Cell Biol. 2000 Dec;20(24):9364-75. doi: 10.1128/MCB.20.24.9364-9375.2000. Mol Cell Biol. 2000. PMID: 11094087 Free PMC article.

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