Clancy DM - Search Results

1

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation.

Sullivan GP, Davidovich PB, Sura-Trueba S, Belotcerkovskaya E, Henry CM, Clancy DM, Zinoveva A, Mametnabiev T, Garabadzhiu AV, Martin SJ. Sullivan GP, et al. Among authors: clancy dm. FEBS Open Bio. 2018 Mar 25;8(5):751-763. doi: 10.1002/2211-5463.12406. eCollection 2018 May. FEBS Open Bio. 2018. PMID: 29744290 Free PMC article.

2

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.

Kearney CJ, Cullen SP, Clancy D, Martin SJ. Kearney CJ, et al. FEBS J. 2014 Nov;281(21):4921-34. doi: 10.1111/febs.13034. Epub 2014 Oct 4. FEBS J. 2014. PMID: 25195660 Free article.

3

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.

Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC, Martin SJ. Kearney CJ, et al. Cell Death Differ. 2015 Aug;22(8):1313-27. doi: 10.1038/cdd.2014.222. Epub 2015 Jan 23. Cell Death Differ. 2015. PMID: 25613374 Free PMC article.

4

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis.

Cullen SP, Kearney CJ, Clancy DM, Martin SJ. Cullen SP, et al. Among authors: clancy dm. Cell Rep. 2015 Jun 16;11(10):1535-48. doi: 10.1016/j.celrep.2015.05.003. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027935 Free article.

5

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines.

Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D, Martin SJ. Henry CM, et al. Among authors: clancy dm. Cell Rep. 2016 Feb 2;14(4):708-722. doi: 10.1016/j.celrep.2015.12.072. Epub 2016 Jan 14. Cell Rep. 2016. PMID: 26776523 Free article.

6

Production of biologically active IL-36 family cytokines through insertion of N-terminal caspase cleavage motifs.

Clancy DM, Henry CM, Davidovich PB, Sullivan GP, Belotcerkovskaya E, Martin SJ. Clancy DM, et al. FEBS Open Bio. 2016 Mar 12;6(4):338-48. doi: 10.1002/2211-5463.12044. eCollection 2016 Apr. FEBS Open Bio. 2016. PMID: 27239446 Free PMC article.

7

Getting a gRIP on Flu by Casting the DAI.

Clancy DM, Martin SJ. Clancy DM, et al. Cell Host Microbe. 2016 Nov 9;20(5):552-554. doi: 10.1016/j.chom.2016.10.013. Cell Host Microbe. 2016. PMID: 27832584 Free article.

8

Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines.

Clancy DM, Henry CM, Sullivan GP, Martin SJ. Clancy DM, et al. FEBS J. 2017 Jun;284(11):1712-1725. doi: 10.1111/febs.14075. Epub 2017 Apr 26. FEBS J. 2017. PMID: 28374518 Free article.

9

Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases.

Sullivan GP, Henry CM, Clancy DM, Mametnabiev T, Belotcerkovskaya E, Davidovich P, Sura-Trueba S, Garabadzhiu AV, Martin SJ. Sullivan GP, et al. Among authors: clancy dm. Cell Death Dis. 2018 Mar 7;9(3):378. doi: 10.1038/s41419-018-0385-4. Cell Death Dis. 2018. PMID: 29515113 Free PMC article. Clinical Trial.

10

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.

Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ. Clancy DM, et al. Cell Rep. 2018 Mar 13;22(11):2937-2950. doi: 10.1016/j.celrep.2018.02.062. Cell Rep. 2018. PMID: 29539422 Free article.

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