Rodrigues AD - Search Results

1

A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers.

Rago B, Tierney B, Rodrigues AD, L Holliman C, Ramanathan R. Rago B, et al. Among authors: rodrigues ad. Bioanalysis. 2018 May 1;10(9):645-657. doi: 10.4155/bio-2017-0274. Epub 2018 May 11. Bioanalysis. 2018. PMID: 29749252

2

Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide.

Varma MV, Lin J, Bi YA, Kimoto E, Rodrigues AD. Varma MV, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2015 Jul;43(7):1108-18. doi: 10.1124/dmd.115.064303. Epub 2015 May 4. Drug Metab Dispos. 2015. PMID: 25941268

3

A highly selective and sensitive LC-MS/HRMS assay for quantifying coproporphyrins as organic anion-transporting peptide biomarkers.

Ramanathan R, King-Ahmad AJ, Holliman CL, Rodrigues AD. Ramanathan R, et al. Among authors: rodrigues ad. Bioanalysis. 2017 Nov;9(22):1787-1806. doi: 10.4155/bio-2017-0181. Epub 2017 Oct 5. Bioanalysis. 2017. PMID: 28978230

4

Role of Hepatic Organic Anion Transporter 2 in the Pharmacokinetics of R- and S-Warfarin: In Vitro Studies and Mechanistic Evaluation.

Bi YA, Lin J, Mathialagan S, Tylaska L, Callegari E, Rodrigues AD, Varma MVS. Bi YA, et al. Among authors: rodrigues ad. Mol Pharm. 2018 Mar 5;15(3):1284-1295. doi: 10.1021/acs.molpharmaceut.7b01108. Epub 2018 Feb 20. Mol Pharm. 2018. PMID: 29433307

5

A fully automated and validated human plasma LC-MS/MS assay for endogenous OATP biomarkers coproporphyrin-I and coproporphyrin-III.

King-Ahmad A, Clemens S, Ramanathan R, Zhang Y, Raha N, Zhang Y, Holliman C, Rodrigues AD, Li F. King-Ahmad A, et al. Among authors: rodrigues ad. Bioanalysis. 2018 May 1;10(9):691-701. doi: 10.4155/bio-2017-0270. Epub 2018 May 11. Bioanalysis. 2018. PMID: 29747517

6

LC-MS/MS assay for N¹-methylnicotinamide in humans, an endogenous probe for renal transporters.

Luo L, Kay J, Zhang J, Holliman CL, Rodrigues AD, Dowty M, Banfield C, Ramanathan R. Luo L, et al. Among authors: rodrigues ad. Bioanalysis. 2018 May 1;10(9):673-689. doi: 10.4155/bio-2017-0272. Epub 2018 May 11. Bioanalysis. 2018. PMID: 29749253

7

Endogenous probes for human liver organic anion-transporting polypeptides: the intersection of bioanalytical and ADME science.

Rodrigues AD. Rodrigues AD. Bioanalysis. 2018 May 1;10(9):615-618. doi: 10.4155/bio-2017-0201. Epub 2018 May 16. Bioanalysis. 2018. PMID: 29768033 No abstract available.

8

Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey.

Kosa RE, Lazzaro S, Bi YA, Tierney B, Gates D, Modi S, Costales C, Rodrigues AD, Tremaine LM, Varma MV. Kosa RE, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2018 Aug;46(8):1179-1189. doi: 10.1124/dmd.118.081794. Epub 2018 Jun 7. Drug Metab Dispos. 2018. PMID: 29880631

9

PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3.

Yoshikado T, Toshimoto K, Maeda K, Kusuhara H, Kimoto E, Rodrigues AD, Chiba K, Sugiyama Y. Yoshikado T, et al. Among authors: rodrigues ad. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):739-747. doi: 10.1002/psp4.12348. Epub 2018 Sep 30. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30175555 Free PMC article.

10

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.

Kimoto E, Vourvahis M, Scialis RJ, Eng H, Rodrigues AD, Varma MVS. Kimoto E, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2019 May;47(5):493-503. doi: 10.1124/dmd.118.085241. Epub 2019 Mar 12. Drug Metab Dispos. 2019. PMID: 30862625

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